36-008
Anti-α-Synuclein (SNCA) Antibody
UPSTATE®, mouse monoclonal, Syn211
别名:
Anti-NACP, Anti-PARK1, Anti-PARK4, Anti-PD1
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关于此项目
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
Syn211, monoclonal
Species reactivity:
human
Application:
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Technique(s):
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Citations:
29
Uniprot accession no.:
产品名称
抗α-突触核蛋白抗体，克隆Syn211, ascites fluid, clone Syn211, Upstate®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
Syn211, monoclonal
species reactivity
human
packaging
antibody small pack of 25 μL
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SNCA(6622)
Analysis Note
通过免疫印迹对阿尔茨海默氏病患病的人全脑裂解液进行了常规评估。
Application
使用该抗 α-突触核蛋白抗体（克隆Syn211，经验证可用于 IP、WB、IH）检测 α-突触核蛋白。
研究子类别
神经退行性疾病
神经退行性疾病
研究类别
神经科学
神经科学
Biochem/physiol Actions
α-突触核蛋白
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
~14.5kDa
Immunogen
全长重组人 α-突触核蛋白
Physical form
腹水
Preparation Note
在 -20°C 条件下可保存 2 年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Jay S Schneider et al.
Molecular and cellular neurosciences, 120, 103729-103729 (2022-04-22)
Among the pathological events associated with the dopaminergic neurodegeneration characteristic of Parkinson's disease (PD) are the accumulation of toxic forms of α-synuclein and microglial activation associated with neuroinflammation. Although numerous other processes may participate in the pathogenesis of PD, the
Sarah M O'Donovan et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 32(1), e13726-e13726 (2019-10-03)
A hallmark feature of Parkinson's disease (PD) is the build-up of α-synuclein protein aggregates throughout the brain; however α-synuclein is also expressed in enteric neurons. Gastrointestinal (GI) symptoms and pathology are frequently reported in PD, including constipation, increased intestinal permeability
Neuron-to-neuron ?-synuclein propagation in vivo is independent of neuronal injury.
Ulusoy, A; Musgrove, RE; Rusconi, R; Klinkenberg, M; Helwig, M; Schneider, A; Di Monte, DA
Acta Neuropathologica Communications null
Characterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectors.
Hall, H; Jewett, M; Landeck, N; Nilsson, N; Schagerlof, U; Leanza, G; Kirik, D
Testing null
Sandra Cuellar-Baena et al.
Journal of neurochemistry, 137(5), 806-819 (2016-01-27)
In this study, we used proton-localized spectroscopy ((1) H-MRS) for the acquisition of the neurochemical profile longitudinally in a novel rat model of human wild-type alpha-synuclein (α-syn) over-expression. Our goal was to find out if the increased α-syn load in
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