36-011
抗硝基-α/β-突触核蛋白抗体，克隆nSyn12
clone nSyn12, Upstate®, from mouse
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
nSyn12, monoclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
22
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
nSyn12, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
shipped in
dry ice
Quality Level
Gene Information
human ... SNCA(6622)
General description
α-突触核蛋白，Mr 14.5 kDa
β-突触核蛋白，Mr 17kDa
β-突触核蛋白，Mr 17kDa
Application
抗硝基α/β突触核蛋白抗体，克隆nSyn12是用于WB、IH的抗硝基α/β突触核蛋白抗体。
Biochem/physiol Actions
α-在Tyr125和Tyr136硝化的突触核蛋白
β-在Tyr130硝化的突触核蛋白
β-在Tyr130硝化的突触核蛋白
Physical form
形式：未纯化
Analysis Note
对体外硝化的重组蛋白进行常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Ashley D Reynolds et al.
Journal of neurochemistry, 104(6), 1504-1525 (2007-11-27)
Microglial neuroinflammatory processes play a primary role in dopaminergic neurodegeneration for Parkinson's disease (PD). This can occur, in part, by modulation of glial function following activation by soluble or insoluble modified alpha-synuclein (alpha-syn), a chief component of Lewy bodies that
Bregje W M de Wildt et al.
Biotechnology and bioengineering, 120(7), 2013-2026 (2023-05-06)
The transition in the field of bone tissue engineering from bone regeneration to in vitro models has come with the challenge of recreating a dense and anisotropic bone-like extracellular matrix (ECM). Although the mechanism by which bone ECM gains its
B I Giasson et al.
The Journal of biological chemistry, 274(12), 7619-7622 (1999-03-13)
alpha-Synuclein is a soluble presynaptic protein which is pathologically redistributed within intracellular lesions characteristic of several neurodegenerative diseases. Here we demonstrate that wild type and two mutant forms of alpha-synuclein linked to familial Parkinson's disease (Ala30 --> Pro and Ala53
J M Souza et al.
The Journal of biological chemistry, 275(24), 18344-18349 (2000-04-05)
Intracellular proteinaceous aggregates are hallmarks of many common neurodegenerative disorders, and recent studies have shown that alpha-synuclein is a major component of several pathological intracellular inclusions, including Lewy bodies in Parkinson's disease (PD) and glial cell inclusions in multiple system
Nicole Willems et al.
BMC veterinary research, 12, 10-10 (2016-01-14)
Intervertebral disc (IVD) disease is a common spinal disorder in dogs and degeneration and inflammation are significant components of the pathological cascade. Only limited studies have studied the cytokine and chemokine profiles in IVD degeneration in dogs, and mainly focused
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