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Merck
CN

36-012

抗硝基-α/β-突触核蛋白(Tyr39)抗体,克隆nSyn14

clone nSyn14, Upstate®, from mouse

别名:

Anti-NACP, Anti-PARK4, Anti-PD1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
nSyn14, monoclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
21
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biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

nSyn14, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

nitration (Tyr39)

Gene Information

human ... SNCA(6622)

General description

α-突触核蛋白,Mr 14.5 kDa
β-突触核蛋白,Mr 17kDa

Immunogen

全长重组人体外硝化的α-突触核蛋白

Application

抗硝基-α/β-突触核蛋白(Tyr39)抗体,克隆nSyn14检测硝基-α/β-突触核蛋白(Tyr39)水平&已发表 & 经验证可用于WB,IH。
研究子类别
神经退行性疾病
研究类别
神经科学

Biochem/physiol Actions

α-或β-Tyr39硝化的突触核蛋白

Physical form

含0.05%叠氮化钠的腹水
形式:纯化
腹水

Preparation Note

在-20°C下可保存2年

Analysis Note

通过免疫印迹对体外硝化的重组蛋白进行常规评估

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

10 - Combustible liquids

wgk

WGK 1



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Hugo Vicente Miranda et al.
Scientific reports, 7(1), 13713-13713 (2017-10-24)
Parkinson's disease (PD) is a progressive neurodegenerative disorder known for the typical motor features associated. Pathologically, it is characterized by the intracellular accumulation of alpha-synuclein (aSyn) in Lewy bodies and Lewy neurites. Currently, there are no established biochemical markers for
Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
Duda, J. E., et al
Annals of Neurology, 52, 205-210 (2002)
Emilio Fernández et al.
Antioxidants & redox signaling, 21(15), 2143-2148 (2014-08-16)
The research group has detected nitrosative stress and a singular version of nitrosylated serum α-synuclein in serum of Parkinson's disease (PD) patients. Dysfunction of the thyroid gland has been proposed to be linked to this disease. The aim of the



全球贸易项目编号

货号GTIN
36-01204053252331893