产品名称
抗硝基-α/β-突触核蛋白（Tyr39）抗体，克隆nSyn14, clone nSyn14, Upstate®, from mouse
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
nSyn14, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
shipped in
dry ice
target post-translational modification
nitration (Tyr39)
Quality Level
Gene Information
human ... SNCA(6622)
Analysis Note
通过免疫印迹对体外硝化的重组蛋白进行常规评估
Application
抗硝基-α/β-突触核蛋白（Tyr39）抗体，克隆nSyn14检测硝基-α/β-突触核蛋白（Tyr39）水平&已发表 & 经验证可用于WB，IH。
研究子类别
神经退行性疾病
神经退行性疾病
研究类别
神经科学
神经科学
Biochem/physiol Actions
α-或β-Tyr39硝化的突触核蛋白
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
α-突触核蛋白，Mr 14.5 kDa
β-突触核蛋白，Mr 17kDa
β-突触核蛋白，Mr 17kDa
Immunogen
全长重组人体外硝化的α-突触核蛋白
Physical form
含0.05％叠氮化钠的腹水
形式：纯化
腹水
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Pedro Magalhães et al.
NPJ Parkinson's disease, 8(1), 93-93 (2022-07-23)
Parkinson's disease (PD), the second most common progressive neurodegenerative disease, develops and progresses for 10-15 years before the clinical diagnostic symptoms of the disease are manifested. Furthermore, several aspects of PD pathology overlap with other neurodegenerative diseases (NDDs) linked to
Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
Duda, J. E., et al
Annals of Neurology, 52, 205-210 (2002)
Hugo Vicente Miranda et al.
Scientific reports, 7(1), 13713-13713 (2017-10-24)
Parkinson's disease (PD) is a progressive neurodegenerative disorder known for the typical motor features associated. Pathologically, it is characterized by the intracellular accumulation of alpha-synuclein (aSyn) in Lewy bodies and Lewy neurites. Currently, there are no established biochemical markers for
J M Souza et al.
The Journal of biological chemistry, 275(24), 18344-18349 (2000-04-05)
Intracellular proteinaceous aggregates are hallmarks of many common neurodegenerative disorders, and recent studies have shown that alpha-synuclein is a major component of several pathological intracellular inclusions, including Lewy bodies in Parkinson's disease (PD) and glial cell inclusions in multiple system
Emilio Fernández et al.
Antioxidants & redox signaling, 21(15), 2143-2148 (2014-08-16)
The research group has detected nitrosative stress and a singular version of nitrosylated serum α-synuclein in serum of Parkinson's disease (PD) patients. Dysfunction of the thyroid gland has been proposed to be linked to this disease. The aim of the
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