产品名称
抗整合素β₆ 小鼠单克隆抗体(442.5C4), liquid, clone 442.5C4, Calbiochem®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
442.5C4, monoclonal
form
liquid
does not contain
preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(ELISA
Flow Cytometry (1:50-1:100)
Immunoblotting (1:50-1:100)
Immunoprecipitation (1:50-1:100)
Paraffin Sections (1:50-1:100))
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGB6(3694)
Application
ELISA(见备注)
流式细胞术(1:50-1:100)
免疫印迹(1:50-1:100)
免疫沉淀(1:50-1:100)
石蜡切片(1:50-1:100)
流式细胞术(1:50-1:100)
免疫印迹(1:50-1:100)
免疫沉淀(1:50-1:100)
石蜡切片(1:50-1:100)
Disclaimer
毒性:标准处理(A)
General description
小鼠单克隆抗体以未稀释的腹水形式提供。识别β6 整合素链。
识别β6 整合素链。
该抗整合素β₆小鼠mAb(442.5 C4)经验证可用于ELISA、FC、免疫印迹、IP、石蜡切片,以检测整合素β₆。
Immunogen
人
重组人αvβ₆
Other Notes
Miller, L.A., et al. 2001.J. Histochem.Cytochem.49, 41.
Breuss, J.M., et al. 1995.J. Cell Sci.108, 2241.
Hynes, R.O.1992.Cell.69, 11.
Albelda, S.M. and Buck, C.A.1990.FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F.1987.Ann.Rev. Cell Biol.3, 179.
Hynes, R.O.1987.Cell.45, 549.
Breuss, J.M., et al. 1995.J. Cell Sci.108, 2241.
Hynes, R.O.1992.Cell.69, 11.
Albelda, S.M. and Buck, C.A.1990.FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F.1987.Ann.Rev. Cell Biol.3, 179.
Hynes, R.O.1987.Cell.45, 549.
据报道,该抗体也可用于ELISA。合适的工作稀释度由与测定条件相关的变量决定。
Physical form
未稀释的腹水。
Preparation Note
初次融化后,等分并冷冻(-20°C)。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
EANM'16.
European journal of nuclear medicine and molecular imaging, 43(Suppl 1), 1-734 (2016-09-22)
Johannes Notni et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 58(4), 671-677 (2016-12-17)
Expression of the cellular transmembrane receptor αvβ6 integrin is essentially restricted to malignant epithelial cells in carcinomas of a broad variety of lineages, whereas it is virtually absent in normal adult tissues. Thus, it is a highly attractive target for
Ludmila Prudkin et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(5), 668-678 (2009-03-10)
Epithelial-to-mesenchymal transition is a process in which cells undergo a developmental switch from an epithelial to a mesenchymal phenotype. We investigated the role of this phenomenon in the pathogenesis and progression of adenocarcinoma and squamous cell carcinoma of the lung.
Poster Presentations.
Journal of labelled compounds & radiopharmaceuticals, 60 Suppl 1, 111-640 (2017-05-16)
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