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Merck
CN

407317

抗整合素β₆ 小鼠单克隆抗体(442.5C4)

liquid, clone 442.5C4, Calbiochem®

别名:

Integrin β₆检测抗体, 小鼠Anti-Integrin β₆

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关于此项目

NACRES:
NA.43
UNSPSC Code:
12352203
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产品名称

抗整合素β₆ 小鼠单克隆抗体(442.5C4), liquid, clone 442.5C4, Calbiochem®

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

442.5C4, monoclonal

form

liquid

does not contain

preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(ELISA
Flow Cytometry (1:50-1:100)
Immunoblotting (1:50-1:100)
Immunoprecipitation (1:50-1:100)
Paraffin Sections (1:50-1:100))

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ITGB6(3694)

Application

ELISA(见备注)

流式细胞术(1:50-1:100)

免疫印迹(1:50-1:100)

免疫沉淀(1:50-1:100)

石蜡切片(1:50-1:100)

Disclaimer

毒性:标准处理(A)

General description

小鼠单克隆抗体以未稀释的腹水形式提供。识别β6 整合素链。
识别β6 整合素链。
该抗整合素β₆小鼠mAb(442.5 C4)经验证可用于ELISA、FC、免疫印迹、IP、石蜡切片,以检测整合素β₆。

Immunogen

重组人αvβ₆

Other Notes

Miller, L.A., et al. 2001.J. Histochem.Cytochem.49, 41.
Breuss, J.M., et al. 1995.J. Cell Sci.108, 2241.
Hynes, R.O.1992.Cell.69, 11.
Albelda, S.M. and Buck, C.A.1990.FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F.1987.Ann.Rev. Cell Biol.3, 179.
Hynes, R.O.1987.Cell.45, 549.
据报道,该抗体也可用于ELISA。合适的工作稀释度由与测定条件相关的变量决定。

Physical form

未稀释的腹水。

Preparation Note

初次融化后,等分并冷冻(-20°C)。

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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EANM'16.
European journal of nuclear medicine and molecular imaging, 43(Suppl 1), 1-734 (2016-09-22)
Johannes Notni et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 58(4), 671-677 (2016-12-17)
Expression of the cellular transmembrane receptor αvβ6 integrin is essentially restricted to malignant epithelial cells in carcinomas of a broad variety of lineages, whereas it is virtually absent in normal adult tissues. Thus, it is a highly attractive target for
Ludmila Prudkin et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(5), 668-678 (2009-03-10)
Epithelial-to-mesenchymal transition is a process in which cells undergo a developmental switch from an epithelial to a mesenchymal phenotype. We investigated the role of this phenomenon in the pathogenesis and progression of adenocarcinoma and squamous cell carcinoma of the lung.
Poster Presentations.
Journal of labelled compounds & radiopharmaceuticals, 60 Suppl 1, 111-640 (2017-05-16)

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