Merck
CN
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420355

Sigma-Aldrich

盐酸异丙肾上腺素

Phenethylamine derivative.

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别名:
盐酸异丙肾上腺素
Empirical Formula (Hill Notation):
C11H17NO3 · xHCl
CAS号:
分子量:
211.26 (free base basis)
MDL编号:

质量水平

检测方案

≥99% (TLC)

形式

solid

manufacturer/tradename

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

white to off-white
white

溶解性

ethanol: soluble
water: soluble

运输

ambient

储存温度

10-30°C

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI key

IROWCYIEJAOFOW-UHFFFAOYSA-N

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此商品
1351005215921129876
Isoproterenol, Hydrochloride Phenethylamine derivative.

Sigma-Aldrich

420355

盐酸异丙肾上腺素

Isoproterenol hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1351005

异丙肾上腺素 盐酸盐

Amiloride, Hydrochloride An inhibitor of angiogenesis.

Sigma-Aldrich

129876

盐酸阿霉素

form

solid

form

-

form

crystalline solid

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

USP

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

color

white to off-white

color

-

color

off-white

color

off-white to yellow

solubility

ethanol: soluble, water: soluble

solubility

-

solubility

methanol: 10 mg/mL, water: 50 mg/mL

solubility

water: 2.5 mg/mL, DMSO: 5 mg/mL

一般描述

苯乙胺衍生物。一种刺激腺苷酸环化酶活性的选择性β-肾上腺素能激动剂。促进糖原分解并引起支气管扩张。通过产生一氧化氮增加兔气管细胞中Cl的扩散和电位差。据报道,通过Rap1和B-Raf依赖性过程激活MAP激酶(ERK)。
苯乙胺衍生物。一种增加胞质cAMP的选择性β-肾上腺素能激动剂。促进糖原分解并引起支气管扩张。通过产生一氧化氮增加兔气管细胞中Cl-的扩散和电位差。

生化/生理作用

主要靶标
β肾上腺素能激动剂
产物不与ATP竞争。
可逆:否
细胞渗透性:否

警告

毒性:刺激性(B)

重悬

溶液中不稳定;仅在使用前进行复溶。

其他说明

Schmitt, J.M., and Stork, P.J.2000.J. Biol. Chem.275, 25342.
Carmena, M.J., et al. 1997.Prostate 33, 46.
Takemura, H., et al. 1995.J. Pharmacol.Exp.Ther.274, 584.
Kishimoto, I., et al. 1994.J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994.Mol.Cell Biochem.141, 27.
Yashiro, K., et al. 1994.J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993.J. Neurochem.60, 260.
von Zastrow, M., et al. 1993.J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985.J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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