480708
α2-3，6-神经氨酸酶，产气荚膜梭菌，重组，大肠埃希菌
别名:
α2-3，6-神经氨酸酶，产气荚膜梭菌，重组，大肠埃希菌
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关于此项目
化学文摘社编号:
NACRES:
NA.54
UNSPSC Code:
12352202
MDL number:
Specific activity:
≥10 units/mL, ≥250 units/mg protein
Recombinant:
expressed in E. coli
recombinant
expressed in E. coli
description
RTECS - QQ3450000
product line
EMPROVE® EXPERT
form
liquid
specific activity
≥10 units/mL, ≥250 units/mg protein
manufacturer/tradename
Calbiochem®
storage condition
do not freeze
foreign activity
N-acetylglucosaminidase, α-fucosidase, α- and β-galactosidase, α- and β-mannosidase, proteases, none detected
shipped in
wet ice
Quality Level
General description
注意：1 mU = 1毫单位。
重组产气荚膜梭菌 α2-3，6-神经氨酸酶在大肠埃希菌中表达。对来自复合碳水化合物和糖蛋白类的非还原性末端α2，3和α2，6无支链唾液酸残基的水解进行催化。该酶对α2，8或支链唾液酸不显示活性。
Application
推荐的反应缓冲液：50mM磷酸钠缓冲液，pH 6.0
Physical form
在 25 mM NaCl，20 mM Tris-HCl，pH 7.5中。
Other Notes
Prime, S., et al. 1996.J. Chromatogr. A. 720, 263.
Dwek, R.A., et al. 1993.Annu.Rev. Biochem.62, 65.
Ohta, Y., et al. 1989.J. Biochem (Tokyo) 106, 1086.
Dwek, R.A., et al. 1993.Annu.Rev. Biochem.62, 65.
Ohta, Y., et al. 1989.J. Biochem (Tokyo) 106, 1086.
一个单位定义为在37°C，pH值5.0下每分钟从2ʹ-（4-甲基伞形酮）-α-D-N-乙酰神经氨酸（目录号474495）催化释放1µmol甲基伞形酮的酶量。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：有害（C）
signalword
Warning
Hazard Classifications
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
8B - Non-combustible, corrosive hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Yi Yang et al.
International journal of molecular sciences, 21(22) (2020-11-19)
Polysialic acid (polySia/PSA) is a linear homopolymer of sialic acid (Sia) that primarily modifies the neural cell adhesion molecule (NCAM) in mammalian brains. PolySia-NCAM not only displays an anti-adhesive function due to the hydration effect, but also possesses a molecule-retaining
Airi Mori et al.
International journal of molecular sciences, 21(16) (2020-08-23)
Polysialic acid (polySia/PSA) is an anionic glycan polymer of sialic acid, and it mostly modifies the neural cell adhesion molecule (NCAM) in mammalian brains. Quality and quantity of the polySia of the polySia-NCAM is spatio-temporally regulated in normal brain development
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