489350
L-(−)-Norepinephrine (+)-bitartrate salt monohydrate
≥97% (LC/MS), α,β-Adrenergic agonist, crystalline solid
别名:
L-(−)-Norepinephrine-(+)-bitartrate salt monohydrate, R(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline
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关于此项目
经验公式（希尔记法）:
C8H11NO3 · C4H6O6 · H2O
化学文摘社编号:
分子量:
337.28
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥97% (LC/MS)
Form:
crystalline solid
Quality level:
Storage condition:
OK to freeze
desiccated
desiccated
产品名称
L-(–)-Norepinephrine-(+)-bitartrate, α,β-Adrenergic agonist.
SMILES string
NC[C@H](O)c1cc(c(cc1)O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O
InChI
1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
InChI key
LNBCGLZYLJMGKP-LUDZCAPTSA-N
description
Merck USA index - 14, 6695
assay
≥97% (LC/MS)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
white
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Cell permeable: no
Primary Target
α,β-Adrenergic agonist
α,β-Adrenergic agonist
Product does not compete with ATP.
Reversible: no
Disclaimer
Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)
General description
α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors. Oxidation sensitive.
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Yang, H., et al. 1996. Hypertension 27, 1277.
Preparation Note
Addition of sodium bisulfite (at a final concentration of 0.1%) is necessary to prevent oxidation.
Following reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
H Yang et al.
Hypertension (Dallas, Tex. : 1979), 27(6), 1277-1283 (1996-06-01)
Norepinephrine causes downregulation of angiotensin II (Ang II) receptors in Wistar-Kyoto rat (WKY) brain neuronal cultures. The aim of this study was to compare the cross talk between Ang II and alpha1-adrenergic receptors in these neuronal cultures. Norepinephrine causes a
Inbal Rachmin et al.
Experimental dermatology, 30(4), 578-587 (2021-02-19)
Hair greying depends on the altered presence and functionality of hair follicle melanocytes. Melanocyte stem cells (MelSCs) reside in the bulge of hair follicles and give rise to migrating and differentiating progeny during the anagen phase. Ageing, genotoxic stress, redox
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