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Merck
CN

5.01890

维生素 K₁（叶绿醌）

EMPROVE® ESSENTIAL Ph Eur,BP,USP,FCC

别名:

Vitamin K₁ (phytomenadione), 2-Methyl-3-phytyl-1,4-naphthoquinone

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关于此项目

经验公式（希尔记法）:
C31H46O2
化学文摘社编号:
84-80-0
分子量:
450.70
UNSPSC Code:
12352115
EC Index Number:
201-564-2
MDL number:
MFCD00214063

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SMILES string

O=C1c2c(cccc2)C(=O)C(=C1C\C=C(\CCCC(CCCC(CCCC(C)C)C)C)/C)C

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+

InChI key

MBWXNTAXLNYFJB-LKUDQCMESA-N

agency

BP, Ph. Eur., USP

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

liquid

potency

>33487 mg/kg LD50, oral (Rat)

bp

140-145 °C/0.0013 hPa

mp

-20 °C

transition temp

flash point >109.9 °C

density

0.97 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical

storage temp.

15-25°C

Quality Level

500

相关类别

General description

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Vitamin K1 (phytomenadione) Emprove® Essential is suitable for pharmaceutical applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

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Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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