Merck
CN

8.17007

SAFC

聚乙二醇 溶液

6000, EMPROVE® ESSENTIAL, Ph. Eur.

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别名:
聚(乙二醇), PEG
线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL编号:
EC索引号:
500-038-2

Agency

Ph. Eur.

质量水平

蒸汽压

<0.01 hPa ( 20 °C)

产品线

EMPROVE® ESSENTIAL

形式

solid

自燃温度

420 °C

分子量

average Mn 6000

技术

API processing | nano-milling: suitable

pH值(酸碱度)

5-7 (20 °C, 100 g/L in H2O)

mp

58-63 °C

转变温度

flash point 270 °C

溶解性

550 g/L

密度

1.2 g/cm3 at 20 °C

应用

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

储存温度

15-25°C

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般描述

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Polyethylene glycol (PEG) is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations. Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more. Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

281.5 °F - closed cup

闪点(°C)

138.6 °C - closed cup


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3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

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