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About This Item
经验公式(希尔记法):
C21H23NO4
CAS Number:
分子量:
353.41
MDL编号:
UNSPSC代码:
12352209
EC索引号:
252-662-7
NACRES:
NA.22
质量水平
产品线
Novabiochem®
方案
≥98% (TLC)
≥98.0% (acidimetric)
≥99.0% (HPLC)
表单
powder
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
制造商/商品名称
Novabiochem®
mp
145-153 °C
应用
peptide synthesis
官能团
Fmoc
储存温度
2-30°C
SMILES字符串
N(C(CC(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)
InChI key
CBPJQFCAFFNICX-UHFFFAOYSA-N
一般描述
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of leucine amino-acid residues by Fmoc SPPS
Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS
Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS
应用
- Fmoc-protection efficiency: Addressing the efficiency and recrystallization needs in the Fmoc-protection process (R Yoshino et al., 2017).
- Isotopic labeling for NMR: Development of 17O isotopic labeling of N-Formyl-MLF-OH and related building blocks, enhancing NMR spectroscopy applications (M Ha et al., 2021).
- Perovskite solar cell modification: Investigating the role of Fmoc-Leu-OH in modifying perovskite film to enhance solar cell efficiency (J Song et al., 2022).
分析说明
Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Leu-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Leu-Leu-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Ile-OH (GC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Leu-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Leu-Leu-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Ile-OH (GC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
其他说明
Replaces: 04-12-1025
法律信息
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
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