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关于此项目
经验公式(希尔记法):
C40H33N3O4
化学文摘社编号:
分子量:
619.71
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
Quality Level
product line
Novabiochem®
assay
≥97.0% (acidimetric), ≥98% (TLC), ≥99.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
mp
130-145 °C (decomposition)
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
−20°C (−15°C to −25°C)
SMILES string
[n]4(cnc(c4)C[C@H](NC(=O)OCC5c6c(cccc6)c7c5cccc7)C(=O)O)C(c3ccccc3)(c2ccccc2)c1ccccc1
InChI
1S/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m0/s1
InChI key
XXMYDXUIZKNHDT-QNGWXLTQSA-N
General description
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of histidine amino-acid residues by Fmoc SPPS
Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] P. Sieber, et al. (1987) Tetrahedron Lett., 28, 6031.
Standard building block for introduction of histidine amino-acid residues by Fmoc SPPS
Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] P. Sieber, et al. (1987) Tetrahedron Lett., 28, 6031.
Analysis Note
Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 160 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His(Trt)-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 160 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His(Trt)-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Replaces: 04-12-1065
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
Discover 20 proteinogenic Novabiochem® Fmoc-amino acids, featuring enhanced specifications designed to optimize yields in peptide synthesis.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 8520320025 | 04027269086299 |
| 8520320250 | 04027269207038 |
| 8520320500 | 04027269179878 |
| 8520321000 | 04027269179984 |
| 8520320100 | 04027269086305 |