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About This Item

经验公式(希尔记法):
C35H42N4O7S
CAS Number:
分子量:
662.80
MDL编号:
UNSPSC代码:
12352209
NACRES:
NA.22
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质量水平

产品线

Novabiochem®

方案

≥95.0% (HPLC)

表单

powder

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

Fmoc

储存温度

15-25°C

SMILES字符串

[S](=O)(=O)(N\C(=N\C)\NCCC[C@H](NC(=O)OCC3c4c(cccc4)c5c3cccc5)C(=O)O)c1c(c2c(c(c1C)C)OC(C2)(C)C)C

InChI

1S/C35H42N4O7S/c1-20-21(2)31(22(3)27-18-35(4,5)46-30(20)27)47(43,44)39-33(36-6)37-17-11-16-29(32(40)41)38-34(42)45-19-28-25-14-9-7-12-23(25)24-13-8-10-15-26(24)28/h7-10,12-15,28-29H,11,16-19H2,1-6H3,(H,38,42)(H,40,41)(H2,36,37,39)/t29-/m0/s1

InChI key

JAUPJPAADXVUGQ-LJAQVGFWSA-N

一般描述

A derivative for the introduction of mono-methyl-arginine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Pbf protecting group occurs during the course of the TFA-mediated cleavage reaction. Ref [1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.

联系

Replaces: 04-12-1261

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (DC (018A)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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