8.52227
Fmoc-Pro-OPfp
Novabiochem®
别名:
Fmoc-Pro-OPfp, N-α-Fmoc-L-proline pentafluorophenyl ester
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关于此项目
经验公式（希尔记法）:
C26H18F5NO4
化学文摘社编号:
分子量:
503.42
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
Quality Segment
product line
Novabiochem®
assay
≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
mp
120-130 °C
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
15-25°C
SMILES string
Fc1c(c(c(c(c1F)F)OC(=O)[C@H]2N(CCC2)C(=O)OCC3c4c(cccc4)c5c3cccc5)F)F
InChI
1S/C26H18F5NO4/c27-19-20(28)22(30)24(23(31)21(19)29)36-25(33)18-10-5-11-32(18)26(34)35-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2/t18-/m0/s1
InChI key
CQBLOHXKGUNWRV-SFHVURJKSA-N
General description
Pre-formed pentafluorophenyl ester for coupling of proline amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -64.0 - -57.0 °
DCU (DC (0004)): ≤ 2 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -64.0 - -57.0 °
DCU (DC (0004)): ≤ 2 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Replaces: 04-12-1515
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3