8.52336
Fmoc-Agp(Boc)2-OH
Novabiochem®
别名:
Fmoc-Agp(Boc)2-OH, N-α-Fmoc-N,NÆ-γ-di-t.-butoxycarbonyl-L-diaminobutanoic acid
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选择尺寸
关于此项目
经验公式（希尔记法）:
C29H36N4O8
化学文摘社编号:
分子量:
568.62
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22
产品名称
Fmoc-Agp(Boc)2-OH, Novabiochem®
SMILES string
N([C@@H](CN=C(NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C29H36N4O8/c1-28(2,3)40-26(37)32-24(33-27(38)41-29(4,5)6)30-15-22(23(34)35)31-25(36)39-16-21-19-13-9-7-11-17(19)18-12-8-10-14-20(18)21/h7-14,21-22H,15-16H2,1-6H3,(H,31,36)(H,34,35)(H2,30,32,33,37,38)/t22-/m0/s1
InChI key
KWUNKMXCVKSAEL-QFIPXVFZSA-N
product line
Novabiochem®
assay
≥90.0% (acidimetric)
≥95.0% (HPLC)
≥98% (TLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
Boc
Fmoc
storage temp.
15-25°C
Quality Level
Analysis Note
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.0 %
Optical rotation α 25/D (c=1 in methanol): -12.0 - -8.0 °
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.0 %
Optical rotation α 25/D (c=1 in methanol): -12.0 - -8.0 °
To see the solvent systems used for TLC of Novabiochem® products please click here.
General description
Fmoc-Agb(Boc)2-OH is a useful tool for the introduction of shortened arginine analog, Agb, during Fmoc SPPS. It can be used in exactly the same manner as Fmoc-Arg(Pbf)-OH.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] R. Karstad, et. al. (2012) J. Med. Chem., 55, 6294.
[2] L.Z. Yan, et. al. (2011) , J. Pept. Sci., 17, 383.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] R. Karstad, et. al. (2012) J. Med. Chem., 55, 6294.
[2] L.Z. Yan, et. al. (2011) , J. Pept. Sci., 17, 383.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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