8.52345
Fmoc-Gla(OtBu)2-OH
Novabiochem®
别名:
Fmoc-Gla(OtBu)2-OH, Fmoc-γ-carboxy-Glu(OtBu) 2-OH
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关于此项目
经验公式（希尔记法）:
C29H35NO8
化学文摘社编号:
分子量:
525.59
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22
SMILES string
N([C@@H](CC(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C29H35NO8/c1-28(2,3)37-25(33)21(26(34)38-29(4,5)6)15-23(24(31)32)30-27(35)36-16-22-19-13-9-7-11-17(19)18-12-8-10-14-20(18)22/h7-14,21-23H,15-16H2,1-6H3,(H,30,35)(H,31,32)/t23-/m0/s1
InChI key
XJRUHYXXHXECDI-QHCPKHFHSA-N
product line
Novabiochem®
form
solid
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
carboxylic acid
storage temp.
2-8°C
Quality Level
General description
Fmoc-Gla(OtBu)2-OH is a building block for the introduction of γ-carboxyglutamic acid (Gla). γ -Carboxylation of glutamic acid is a rare post-translational modification that occurs in blood coagulation factors and in some snake and cone snail venoms [1].
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] P. K. Bandyopadhyay (2002) Proc. Natl. Acad. Sci. USA, 99, 1264 .
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] P. K. Bandyopadhyay (2002) Proc. Natl. Acad. Sci. USA, 99, 1264 .
Analysis Note
Colour (visual): white to slight yellow to slight red
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
European Union for cosmetic colour additives.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
European Union for cosmetic colour additives.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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