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Merck
CN

8.55031

Rink Amide NovaGel

Novabiochem®

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NACRES:
NA.22
UNSPSC Code:
12352111
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产品名称

Rink Amide NovaGel, Novabiochem®

product line

NovaGel
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

Quality Level

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

General description

This resin is prepared by derivatization of aminomethyl NovaGel with the modified Rink linker. NovaGel resins combine many of the excellent properties of PEG-PS-based resins with the high loading efficiency of conventional polystyrene-based supports. In a comparison with Rink amide resin, this resin was found to give superior results in the synthesis of peptides up to 17 amino acids in length [1]. The use of this support in the preparation of oligonucleotide-peptide conjugates has been described [2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.50 - 0.70 mmol/g
Swelling Volume (in DMF): lot specific result
The PEG-PS resin is prepared from aminomethyl copoly(styrene-1 % DVB), 100 - 200 mesh

Other Notes

Replaces: 01-64-0286

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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商品

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

实验方案

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

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