product line
Novabiochem®
form
beads
reaction suitability
reaction type: solution phase peptide synthesis, reactivity: alcohol reactive
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
General description
This polymer-bound version of IBX cleanly converts primary and secondary alcohols to the corresponding aldehydes and ketones [1,2]. It is particularly useful for the synthesis of peptide aldehydes as it oxidises peptide alcohols efficiently and spent resin can be simply removed by filtration.
Literature references
[1] G. Sorg, et al. (2001) Angew. Chem. Int. Ed., 40, 4395.
[2] G. Sorg, et al. (2005) J. Pept. Sci.,11, 147.
Literature references
[1] G. Sorg, et al. (2001) Angew. Chem. Int. Ed., 40, 4395.
[2] G. Sorg, et al. (2005) J. Pept. Sci.,11, 147.
Application
- 2-Iodoxybenzoic Acid: An Oxidant for Functional Group Transformations: This study discusses the use of IBX for various organic transformations, including the oxidation of silyl enol ethers and the preparation of polystyrene supported periodinane reagent. (Nair, 2020).
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of iodine): 0.90 - 1.50 mmol/g
Oxidation of Cinnamyl alcohol to Cinnamaldehyde (2 eq. IBX PS): ≥ 90 %
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh.
Appearance of substance (visual): beads
Loading (determined by elemental analysis of iodine): 0.90 - 1.50 mmol/g
Oxidation of Cinnamyl alcohol to Cinnamaldehyde (2 eq. IBX PS): ≥ 90 %
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh.
Other Notes
Replaces: 01-64-0445
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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