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Merck
CN

8.55050

Dansyl NovaTag® resin

Novabiochem®

别名:

N-Dansyl-NÆ-Fmoc-ethylenediamine MPB-AM resin

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关于此项目

NACRES:
NA.22
UNSPSC Code:
12352116
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Quality Level

product line

NovaSyn® TG, Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

15-25°C

General description

Dansyl NovaTag resin is an ideal tool for the synthesis of Dansyl-labeled peptides. The resin pre-loaded with the Dansyl chromophore can be used directly in Fmoc SPPS. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the Dansyl-labeled peptide. This resin has been recently used to dansyl-labeled amyloid-RGD peptides [1] and FRET probes for mercury binding protein MerP [2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] S. L. Gras, et al. (2008) Biomaterials, 29, 1553.
[2] B. R. White, et al. (2008) Analyst,, 133, 65

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 & DVB 100 - 200 mesh

Other Notes

Replaces: 04-12-3900

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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商品

Chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry.





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