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Merck
CN

8.55115

Aminomethylated polystyrene LL (100-200 mesh)

Novabiochem®

别名:

AM resin LL (100-200 mesh)

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关于此项目

NACRES:
NA.22
UNSPSC Code:
13111023
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Quality Segment

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-30°C

General description

Novabiochem® AM resin is prepared according to optimized protocols by direct aminomethylation of polystyrene [1]. This process gives a highly homogeneous and chemically defined support free from potentially reactive chloromethyl groups. This resin can be easily acylated with any appropriate carboxylic acid-containing linker using standard methods of amide bond formation to furnish supports for both Boc and Fmoc batch SPPS and SPOS.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
TNBS-Test (positive): passes test
TNBS-Test (after loading with Fmoc-Leu-OH (negative)): passes test
The polymer matrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

Other Notes

Replaces: 01-64-0447

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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