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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
guinea pig, mouse, rat
Application:
immunohistochemistry
western blot
western blot
Technique(s):
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
Citations:
120
Uniprot accession no.:
产品名称
抗胆碱乙酰基转移酶抗体, serum, Chemicon®
biological source
goat
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
guinea pig, mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Chat(12647)
rat ... Chat(290567)
Analysis Note
对照
大鼠脑组织
大鼠脑组织
Application
免疫印迹:1:1,000-1:5,000
免疫组化:1:500-1:1,000。参见本数据表的第2页。
最佳工作稀释度必须由最终用户进行确定。
免疫组化:1:500-1:1,000。参见本数据表的第2页。
最佳工作稀释度必须由最终用户进行确定。
抗胆碱乙酰基转移酶抗体是抗胆碱乙酰基转移酶的抗体,可用于IH & WB。
研究子类别
神经递质 & 受体
神经元 & 胶质标记
神经递质 & 受体
神经元 & 胶质标记
研究类别
神经科学
神经科学
Biochem/physiol Actions
识别大脑和中枢神经紧张的系统中的胆碱能神经元。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
70 kDa
乙酰胆碱(ACh)是运动神经元、神经节前自主神经元、神经节后副交感神经元、各种大脑区域和一些新兴的神经元样干细胞的常见神经递质。Ach 的代谢相对简单,仅涉及两种酶:用于合成的胆碱乙酰基转移酶(ChAT)和用于降解的乙酰胆碱酯酶(AChE)。此外,乙酰胆碱在除神经传递以外的神经元中几乎没有功能,并且似乎是神经元特异性的。似乎只有胆碱能神经元具有大量的ChAT,使得抗胆碱乙酰基转移酶成为有用的特异性标志物。
Immunogen
人胎盘酶。
Other Notes
浓度:请参考批次特异性浓缩物的检验报告。
Physical form
山羊抗血清,液体,不含防腐剂。
未纯化
Preparation Note
自收到之日起在-20°C可稳定保存1年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始小瓶进行离心。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Aging-related deficits in orexin/hypocretin modulation of the septohippocampal cholinergic system.
Stanley, EM; Fadel, J
Synapse null
Jayakrishnan Nair et al.
Respiratory physiology & neurobiology, 236, 57-68 (2016-11-14)
Limited data are available regarding the spinal projections of afferent fibers in the phrenic nerve. We describe a method that robustly labels phrenic afferent spinal projections in adult rats. The proximal end of the cut phrenic nerve was secured in
Lorelei Stoica et al.
Annals of neurology, 79(4), 687-700 (2016-02-19)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motor neurons, resulting in progressive muscle weakness, paralysis, and death within 5 years of diagnosis. About 10% of cases are inherited, of which 20% are due to
Melissa A Stouffer et al.
Nature communications, 6, 8543-8543 (2015-10-28)
Insulin activates insulin receptors (InsRs) in the hypothalamus to signal satiety after a meal. However, the rising incidence of obesity, which results in chronically elevated insulin levels, implies that insulin may also act in brain centres that regulate motivation and
Fumiyasu Imai et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(21), 5724-5735 (2016-05-27)
Spinal reflex circuit development requires the precise regulation of axon trajectories, synaptic specificity, and synapse formation. Of these three crucial steps, the molecular mechanisms underlying synapse formation between group Ia proprioceptive sensory neurons and motor neurons is the least understood.
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