biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable
shipped in
dry ice
target post-translational modification
unmodified
Immunogen
神经原纤维缠结蛋白,在沸腾的SDS中提取并经蔗糖梯度离心纯化。
Application
抗神经原纤维缠结蛋白抗体是一种针对神经原纤维缠结蛋白的抗体,可用于ELISA、WB、IH和IH(P)。
石蜡、振动切片机和冷冻切片的免疫组织化学:分别为≥1:200、≥1:2,000。
蛋白质印迹:≥1:500.
使用免疫原肽的ELISA:≥1:4,000.
最佳工作稀释度必须由最终用户进行确定。
蛋白质印迹:≥1:500.
使用免疫原肽的ELISA:≥1:4,000.
最佳工作稀释度必须由最终用户进行确定。
研究子类别
神经退行性疾病
神经退行性疾病
研究类别
神经科学
神经科学
Biochem/physiol Actions
在阿尔茨海默氏病、唐氏综合征和正常衰老的人中,使神经原纤维缠结蛋白特异性染色并使斑块神经突退化。
Physical form
兔抗血清,含0.01%硫汞撒
Preparation Note
以未稀释的等分试样保存于-20°C下12个月。应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
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Journal of neuroscience research, 77(1), 35-53 (2004-06-16)
Transgenic expression of interleukin-6 (IL-6) in the CNS under the control of the glial fibrillary acidic protein (GFAP) gene promoter (GFAP-IL6 mice) induces significant inflammation and neurodegeneration but also affords neuroprotection against acute traumatic brain injury. This neuroprotection is likely
Reducing amyloid-related Alzheimer's disease pathogenesis by a small molecule targeting filamin A.
Wang, HY; Bakshi, K; Frankfurt, M; Stucky, A; Goberdhan, M; Shah, SM; Burns, LH
The Journal of Neuroscience null
Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory.
Julio J Ramirez et al.
Behavioural brain research, 216(1), 332-340 (2010-08-24)
Entorhinal cortex neuropathology begins very early in Alzheimer's disease (AD), a disorder characterized by severe memory disruption. Indeed, loss of entorhinal volume is predictive of AD and two of the hallmark neuroanatomical markers of AD, amyloid plaques and neurofibrillary tangles
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AB1518 | 04053252509230 |