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Merck
CN

AB15552

抗-AT1受体抗体

Chemicon®, from rabbit

别名:

Angiotensin II receptory type 1, AGTR1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Species reactivity:
mouse, rat, human
Citations:
14
Technique(s):
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
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产品名称

抗-AT1受体抗体, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... AGTR1(185)

Application

抗AT1受体抗体检测AT1受体的水平 &经发布 & 经验证可用于FC、IC、IH & WB。
研究子类别
新陈代谢的CNS控制

激素 & 受体
研究类别
神经科学
蛋白质印迹:1:200-1:500,使用ECL对大鼠肝脏,大鼠肾脏,小鼠心脏和小鼠肾脏裂解液。
大鼠脑切片上的免疫组化。
免疫细胞化学:1:100
间接流式细胞仪:5-10 µg抗体/1 x 106细胞
应使用载体蛋白如BSA(1-3%)制备稀释液。
最佳工作稀释度必须由最终用户进行确定。

Analysis Note

对照
含有的免费抗体为40 µg对照抗原(冻干粉剂)。 可以使用100 µL无菌去离子水配制抗原储备液。 对于阴性对照,将1 µg肽与1 µg抗体在室温下预孵育1小时。 最佳浓度必须由最终用户进行确定。

Biochem/physiol Actions

在犬中的免疫抗原序列是相同的。
识别AT1受体(血管收缩素II受体1型,AGTR1)。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Immunogen

来自人AT1受体N末端的纯化肽(登录号P30556)。

Physical form

从含有1% BSA和0.05%叠氮化钠(作为防腐剂)的磷酸盐缓冲液(pH7.4)中进行冻干。 用50 μL无菌去离子水复溶。使用前离心抗体制剂(10,000 xg,5 min)。
免疫亲和纯化
形式:纯化

Preparation Note

自收到之日起,冻干材料在-20°C下可保存长达12个月。 复溶后,以未稀释的等分试样在-20°C下可保持长达6个月。 应避免反复冻/融循环。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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hcodes

Hazard Classifications

Aquatic Chronic 3

存储类别

11 - Combustible Solids

wgk

WGK 3


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Francielle Graus-Nunes et al.
World journal of hepatology, 11(4), 359-369 (2019-05-23)
Obesity has been associated with hepatic overexpression of the renin-angiotensin system (RAS). To evaluate the action of two angiotensin II (ANGII) receptor blockers (losartan or telmisartan) on the modulation of local hepatic RAS and the resulting metabolic effects in a
Mehmet Hakan Ozdener et al.
Nutrients, 14(13) (2022-07-10)
In addition to the α, β, and γ subunits of ENaC, human salt-sensing taste receptor cells (TRCs) also express the δ-subunit. At present, it is not clear if the expression and function of the ENaC δ-subunit in human salt-sensing TRCs
Julius Benicky et al.
Cellular and molecular neurobiology, 32(8), 1353-1365 (2012-07-31)
Commercially available Angiotensin II AT1 receptor antibodies are widely employed for receptor localization and quantification, but they have not been adequately validated. In this study, six commercially available AT1 receptor antibodies were characterized by established criteria: sc-1173 and sc-579 from
K Semba et al.
Cell death & disease, 5, e1333-e1333 (2014-07-18)
Glaucoma, one of the leading causes of irreversible blindness, is characterized by progressive degeneration of optic nerves and retinal ganglion cells (RGCs). In the mammalian retina, excitatory amino acid carrier 1 (EAAC1) is expressed in neural cells, including RGCs, and
Hana Sutovska et al.
Experimental physiology, 106(8), 1762-1771 (2021-06-06)
What is the central question of this study? Artificial light at night decreases blood pressure and heart rate in rats. Are these changes in heart rate accompanied by changes in protein expression in the heart's left ventricle? What is the

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