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Merck
CN

AB1569

抗多巴脱羧酶抗体

Chemicon®, from rabbit

别名:

Anti-AADC

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot
Species reactivity:
canine, bovine, rat, guinea pig, human, sheep
Citations:
30
Technique(s):
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
P20711

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产品名称

抗多巴脱羧酶抗体, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

canine, bovine, rat, guinea pig, human, sheep

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_000790.3
NM_001082971.1

UniProt accession no.

P20711

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CDNF(441549)

相关类别

Application

使用经验证可用于IH & WB的抗多巴脱羧酶抗体检测多巴脱羧酶。
免疫印迹：1:500-1:1,000

使用甲醛固定的脑切片进行免疫组化。

最佳工作稀释度必须由最终用户进行确定。
研究子类别
神经递质 & 受体

神经元 & 胶质标记
研究类别
神经科学

Biochem/physiol Actions

DOPA多巴脱羧酶（DDC）。通过蛋白质印迹法与约55 kDa的单条带反应。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Immunogen

重组牛DDC在大肠埃希菌中表达，并从包涵体中纯化。

Other Notes

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

Physical form

亲和纯化的免疫球蛋白。 在10 mM HEPES（pH 7.5），150 mM NaCl，100 μg/mL BSA和50%甘油中的液体。

Preparation Note

自收到之日起，在-20至-80°C以未稀释的等分试样可保存6个月。存放在非自动除霜的冰箱中。应避免反复冻融循环。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

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Diana Marie Battaglia et al.
Frontiers in microbiology, 13, 859866-859866 (2022-04-09)
Herpes simplex virus-associated diseases are a complex interaction between cytolytic viral replication and inflammation. Within the normally avascular and immunoprivileged cornea, HSV ocular infection can result in vision-threatening immune-mediated herpetic keratitis, the leading infectious cause of corneal blindness in the
Branden J Stansley et al.
Neuropharmacology, 67, 243-251 (2012-12-01)
L-dopa is a precursor for dopamine synthesis and a mainstay treatment for Parkinson's disease. However, l-dopa therapy is not without side effects that may be attributed to non-dopaminergic mechanisms. Synthesized dopamine can be neurotoxic through its enzymatic degradation by monoamine
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons.
Hook, V; Brennand, KJ; Kim, Y; Toneff, T; Funkelstein, L; Lee, KC; Ziegler, M; Gage, FH
Stem Cell Reports null
Kara Kaplan et al.
Journal of applied physiology (Bethesda, Md. : 1985), 120(9), 1070-1081 (2016-02-13)
Genetic deletion of brain serotonin (5-HT) neurons in mice leads to ventilatory deficits and increased neonatal mortality during development. However, it is unclear if the loss of the 5-HT neurons or the loss of the neurochemical 5-HT led to the
Erik Cederfjäll et al.
Scientific reports, 3, 2157-2157 (2013-07-09)
We used a single adeno-associated viral (AAV) vector co-expressing tyrosine hydroxylase (TH) and GTP cyclohydrolase 1 (GCH1) to investigate the relationship between vector dose, and the magnitude and rate of recovery in hemi-parkinsonian rats. Intrastriatal injections of >1E10 genomic copies
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