AB1570
抗GABA转运蛋白-1抗体，CT（a.a.588-599）
Chemicon®, from rabbit
别名:
GAT-1
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选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
Species reactivity:
monkey, feline, rat, human, mouse, rabbit
Citations:
33
Technique(s):
immunohistochemistry: suitable
Uniprot accession no.:
产品名称
抗GABA转运蛋白-1抗体，CT（a.a.588-599）, Chemicon®, from rabbit
suitability
not suitable for Western blot
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
monkey, feline, rat, human, mouse, rabbit
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC6A1(6529)
Immunogen
表位：C-端（a.a.588-599）
大鼠GAT-1，C-末端（aa 588-599）
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Biochem/physiol Actions
GABA转运蛋白-1（GAT-1），C末端。没有检测到与其他发射转运蛋白的C末端的交叉反应性。
Application
免疫组化：1:500-1:750，在4%多聚甲醛固定或4%多聚甲醛和0.2%戊二醛固定的组织上。建议用含10%正常山羊血清和0.5%Triton X-100的PBS稀释抗体。AB1570已用于大鼠视网膜、皮层和海马的光学和电子显微镜研究。
注意：不建议将AB1570用于蛋白质印迹。参见AB1570W。
最佳工作稀释度必须由最终用户进行确定。
注意：不建议将AB1570用于蛋白质印迹。参见AB1570W。
最佳工作稀释度必须由最终用户进行确定。
抗GABA转运蛋白-1抗体，C末端（a.a.588-599）是针对GABA转运蛋白-1的抗体，可用于IH。
Physical form
亲和纯化抗体。 从含1%BSA和0.1%叠氮化钠的0.1 M PBS中冻干。用100 μL无菌蒸馏水复溶。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
存储类别
11 - Combustible Solids
wgk
WGK 3
Constantino Sotelo
The Journal of comparative neurology, 506(2), 240-262 (2007-11-21)
The acquisition of the dynamic balance between excitation and inhibition in developing Purkinje cells, necessary for their proper function, is analyzed. Newborn (P0) mouse cerebellum contains glutamatergic (VGLUT2-IR) and gamma-aminobutyric acid (GABA)-ergic (VIAAT-IR) axons. The former prevail and belong to
Muhamed N H Eeza et al.
Journal of Alzheimer's disease : JAD, 81(2), 797-808 (2021-04-13)
Circadian rhythm disturbance is commonly observed in Alzheimer's disease (AD). In mammals, these rhythms are orchestrated by the superchiasmatic nucleus (SCN). Our previous study in the Tg2576 AD mouse model suggests that inflammatory responses, most likely manifested by low GABA
Pericellular innervation of neurons expressing abnormally hyperphosphorylated tau in the hippocampal formation of Alzheimer's disease patients.
Blazquez-Llorca, L; Garcia-Marin, V; Defelipe, J
Frontiers in Neuroanatomy null
Lu Pu et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 818451-818451 (2013-02-01)
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation. Here we investigated regulation of GABA transporter GAT1 by δOR in rats and in
Elena E Bagley et al.
Neuron, 45(3), 433-445 (2005-02-08)
Adaptations in neurons of the midbrain periaqueductal gray (PAG) induced by chronic morphine treatment mediate expression of many signs of opioid withdrawal. The abnormally elevated action potential rate of opioid-sensitive PAG neurons is a likely cellular mechanism for withdrawal expression.
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