产品名称
抗连接蛋白45抗体，近CT，细胞质, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, human, mouse
species reactivity (predicted by homology)
dog (based on 100% sequence homology)
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
dog ... Gjc1(490936)
human ... GJC1(10052)
mouse ... Gjc1(14615)
rat ... Gjc1(266706)
Application
使用经验证可用于IP、WB、IH的细胞质抗间隙连接蛋白45抗体（近C端）检测间隙连接蛋白45。
Biochem/physiol Actions
识别人类，大鼠和小鼠间隙连接蛋白45。由于序列同源性，该抗体也有望与犬间隙连接蛋白45（100%同源）发生反应。其他物种还未经测试。
Immunogen
KLH偶联合成线性肽，对应于人间隙连接蛋白45的C末端附近区域。
Physical form
形式：纯化
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
M Nitta et al.
Journal of animal science, 88(10), 3269-3279 (2010-06-22)
During mammalian oogenesis, intercellular communication between oocytes and the surrounding follicle cells through gap junction channels is crucial for oocyte development and maturation. The channel properties of gap junctions may be affected by the composition or combination of connexins, the
Erika R Kinjo et al.
PloS one, 9(10), e109149-e109149 (2014-10-10)
Gap junction (GJ) channels have been recognized as an important mechanism for synchronizing neuronal networks. Herein, we investigated the participation of GJ channels in the pilocarpine-induced status epilepticus (SE) by analyzing electrophysiological activity following the blockade of connexins (Cx)-mediated communication.
Loïc Le Gal et al.
Journal of the American Heart Association, 8(8), e010823-e010823 (2019-04-05)
Background Gap junction channels made of Connexin37 (Cx37) are expressed by aortic endothelial and smooth muscle cells of hypertensive mice, as well as by the renin-secreting cells of kidneys. Methods and Results To decipher whether Cx37 has any role in
Hanna Langhorst et al.
Disease models & mechanisms, 11(2) (2018-01-24)
CAR-like membrane protein (CLMP), an immunoglobulin cell adhesion molecule (IgCAM), has been implicated in congenital short-bowel syndrome in humans, a condition with high mortality for which there is currently no cure. We therefore studied the function of CLMP in a
Karen Maass et al.
Circulation research, 101(12), 1283-1291 (2007-10-13)
Haplodeficient mice expressing carboxyl-terminally truncated Cx43 (K258stop/KO), instead of the wild-type Cx43 isoform, reach adulthood and reveal no abnormalities in heart morphology. Here, we have analyzed the expression of K258stop protein and the morphology of gap junctions in adult hearts
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