产品名称
抗Prosurfactant蛋白B抗体，可与CT和NT反应, serum, Chemicon®
biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SFTPB(6439)
Application
使用该抗前表面活性物质蛋白B抗体检测前表面活性物质蛋白B，该抗体与经验证可用于ELISA、IH &WB的C末端&N末端均反应。
免疫组化：在有和没有抗原修复的人体组织上为1：4,000-1：8,000（请参见背面的方案），在成年和胎儿小鼠肺上为1：1,000-1：2,000（请参见背面的注释）。
免疫印迹：1:1,000-1:5,000；前蛋白42-46kDa。
ELISA：1:500-1:1,000
最佳稀释度必须由最终用户确定。
免疫印迹：1:1,000-1:5,000；前蛋白42-46kDa。
ELISA：1:500-1:1,000
最佳稀释度必须由最终用户确定。
研究子类别
离子&运输通道
离子&运输通道
研究类别
代谢
代谢
Biochem/physiol Actions
与人和小鼠proSP-B强烈反应（同时检测N末端和C末端前肽）。不与成熟SP-B反应。在人体组织上免疫染色肺泡II型细胞和非纤毛细支气管细胞。在小鼠组织上，免疫染色远端和终末气道中的肺泡II型细胞和非纤毛细支气管（Clara细胞）。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
人SP-B（前）前蛋白的全长重组肽（381 a.a.）。
表位：同时与C末端和N末端反应
Physical form
兔血清。调理液。不含防腐剂。
Preparation Note
以未稀释的等分试样保存于-20°C下12个月。应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Raffaele Gerlini et al.
Cell death & disease, 10(10), 747-747 (2019-10-05)
The serine-threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) modulates important cellular functions during development, acting as a signal integrator of a wide variety of stress signals, and as a regulator of transcription factors and cofactors. We have previously demonstrated that
Shashi P Singh et al.
Environmental health perspectives, 121(8), 957-964 (2013-06-13)
Cigarette smoke (CS) exposure during gestation may increase the risk of bronchopulmonary dysplasia (BPD)-a developmental lung condition primarily seen in neonates that is characterized by hypoalveolarization, decreased angiogenesis, and diminished surfactant protein production and may increase the risk of chronic
Jonathan M Charest et al.
Biomaterials, 52, 79-87 (2015-03-31)
The primary treatment for end-stage lung disease is lung transplantation. However, donor organ shortage remains a major barrier for many patients. In recent years, techniques for maintaining lungs ex vivo for evaluation and short-term (<12 h) resuscitation have come into
Mario DeFelice et al.
The Journal of biological chemistry, 278(37), 35574-35583 (2003-06-28)
Thyroid transcription factor-1 (TTF-1) is a 43-kDa, phosphorylated member of the Nkx2 family of homeodomain-containing proteins expressed selectively in lung, thyroid, and the central nervous system. To assess the role of TTF-1 and its phosphorylation during lung morphogenesis, mice bearing
Sarah E Gilpin et al.
Biomaterials, 108, 111-119 (2016-09-14)
Bio-engineered organs for transplantation may ultimately provide a personalized solution for end-stage organ failure, without the risk of rejection. Building upon the process of whole organ perfusion decellularization, we aimed to develop novel, translational methods for the recellularization and regeneration
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持