产品名称
抗黑素细胞刺激素α抗体, serum, Chemicon®
biological source
sheep
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity (predicted by homology)
mammals
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
radioimmunoassay: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... POMC(5443)
Analysis Note
对照
下丘脑
下丘脑
Application
免疫组化：在4%多聚甲醛固定的组织上为1：10,000-1：50,000。
RIA：1：250,000-1：300,000。
最佳工作稀释度必须由最终用户进行确定。
RIA：1：250,000-1：300,000。
最佳工作稀释度必须由最终用户进行确定。
抗促黑素细胞激素抗体，α检测促黑素细胞激素的水平&已发表&已验证可用于IH，RIA。
研究子类别
代谢的CNS控制
激素&受体
代谢的CNS控制
激素&受体
研究类别
神经科学
神经科学
Biochem/physiol Actions
对α-促黑素细胞激素（aMSH），C-末端具有特异性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
MSH与牛甲状腺球蛋白偶联。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
未纯化
羊血清。 调理液。不含防腐剂。
Preparation Note
自发运之日起在-20°C可保存1年。等分以避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Amanda H Mortensen et al.
Human molecular genetics, 24(4), 939-953 (2014-10-16)
OTX2 is a homeodomain transcription factor that is necessary for normal head development in mouse and man. Heterozygosity for loss-of-function alleles causes an incompletely penetrant, haploinsufficiency disorder. Affected individuals exhibit a spectrum of features that range from developmental defects in
B E Grayson et al.
Endocrinology, 151(4), 1622-1632 (2010-02-24)
The hypothalamic melanocortin system, which controls appetite and energy expenditure, develops during the third trimester in primates. Thus, maternal nutrition and health may have a profound influence on the development of this system. To study the effects of chronic maternal
Fumihiko Maekawa et al.
Frontiers in synaptic neuroscience, 5, 7-7 (2013-10-10)
We previously reported that the type 2 diabetic Goto-Kakizaki (GK) rats at young adult ages (6-12 weeks) exhibited increased visceral fat mass and hyperleptinemia, due to hyperphagia caused primarily by neuropeptide Y (NPY) overexpression in the hypothalamic arcuate nucleus. Later
Maja Cigrovski Berkovic et al.
Neuroendocrinology, 99(2), 75-84 (2014-04-02)
Although previously considered rare, recent epidemiological studies have revealed that the incidence (3.6/100,000) and prevalence (35/100,000) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the past few decades. Despite the progress in the understanding of GEP-NET molecular biology, there is
Angela M Ramos-Lobo et al.
eLife, 8 (2019-01-30)
Leptin regulates energy balance and also exhibits neurotrophic effects during critical developmental periods. However, the actual role of leptin during development is not yet fully understood. To uncover the importance of leptin in early life, the present study restored leptin
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