产品名称
抗神经生成素3抗体（小鼠神经生成素3的a.a. 80-93）, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, rat, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NEUROG3(50674)
Analysis Note
对照
大鼠脑组织
大鼠脑组织
Application
免疫组化：1：200-1：1，000.
免疫细胞化学：货号 # AB5684 以1：500 的稀释度在PC12 细胞中检测到神经生成素3
不推荐用于蛋白质印迹。
免疫细胞化学：货号 # AB5684 以1：500 的稀释度在PC12 细胞中检测到神经生成素3
不推荐用于蛋白质印迹。
抗神经生成素3抗体（小鼠神经生成素3的a.a. 80-93）可检测神经生成素3的水平 & 已有相关文献发表 & 经验证可用于IH。
研究子类别
发育神经科学
神经&胶质标志物
发育神经科学
神经&胶质标志物
研究类别
神经科学
神经科学
Biochem/physiol Actions
可识别神经生成素3（MATH4b），这是一类螺旋-环-螺旋转录因子。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
神经生成素是参与指定神经元分化的bHLH转录因子家族。它们与无调性果蝇有关。神经生成素（ngns）构成了这些与无调性相关的基因家族之一。在神经嵴细胞中，与无调性相关的神经生成素家族对于感觉谱系特别重要（神经生成素对于背根神经节的形成至关重要），而achaete-scute同源物ash1（Mash1）对于自主神经发生方面很重要（Mash1对于去甲肾上腺素能分化至关重要）。神经生成素3促进胰腺发育。
约23 kDa
Immunogen
合成肽，小鼠神经生成素3的氨基酸80-93 。
表位：小鼠神经生成素3的a.a. 80-93
Physical form
亲和纯化的免疫球蛋白。 在不含防腐剂的50%饱和硫酸铵和PBS溶液中沉淀的抗体。
Preparation Note
自收到之日起在-20ºC可稳定保存1年。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Guido Carpino et al.
Journal of anatomy, 228(3), 474-486 (2015-11-28)
Pancreatic duct glands (PDGs) are tubule-alveolar glands associated with the pancreatic duct system and can be considered the anatomical counterpart of peribiliary glands (PBGs) found within the biliary tree. Recently, we demonstrated that endodermal precursor niches exist fetally and postnatally
Junping Wen et al.
Journal of diabetes, 9(7), 707-716 (2016-10-30)
β-Cells at different stages have different functions and capacity for proliferation, regenerative and apoptosis. The aim of the present study was to investigate whether there are changes in β-cell phonotype in the development of diabetes to identify potential β-cell targets
Fang-Xu Jiang et al.
Stem cells (Dayton, Ohio), 35(5), 1341-1354 (2017-01-17)
Developmental stage-specific differentiation of stem or progenitor cells into safe and functional cells is of fundamental importance in regenerative medicine, including β-cell replacement. However, the differentiation of islet progenitor cells (IPCs) into insulin-secreting β cells remains elusive. Here, we report
Tzu-Lei Kuo et al.
iScience, 26(1), 105881-105881 (2023-01-20)
ARID1A is a tumor suppressor gene mutated in 7-10% of pancreatic cancer patients. However, its function in pancreas development and endocrine regulation is unclear. We generated mice that lack Arid1a expression in the pancreas. Our results showed that deletion of
Guido Carpino et al.
Stem cells (Dayton, Ohio), 34(5), 1332-1342 (2016-02-07)
Peribiliary glands (PBGs) are niches in the biliary tree and containing heterogeneous endodermal stem/progenitors cells that can differentiate, in vitro and in vivo, toward pancreatic islets. The aim of this study was to evaluate, in experimental and human diabetes, proliferation
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