AB5935
酪氨酸羟化酶抗体，磷酸化Ser 40
Chemicon®, from rabbit
别名:
Tyrosine Monooxygenase
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
avian, rat, mouse
Application:
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
immunohistochemistry: suitable
western blot: suitable
Citations:
36
Uniprot accession no.:
产品名称
酪氨酸羟化酶抗体，磷酸化Ser 40, Chemicon®, from rabbit
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
avian, rat, mouse
species reactivity (predicted by homology)
quail (100% sequence homology), nonhuman primates (100% sequence homology), human (100% sequence homology), porcine (100% sequence homology)
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pSer40)
Quality Level
Analysis Note
对照
阳性对照：脑（交感神经末梢）和肾上腺。
阳性对照：脑（交感神经末梢）和肾上腺。
通过蛋白质印迹对PC12裂解液进行常规评估。
蛋白质印迹分析：
该批次的1:500稀释液在10 μg PC12裂解液中检测到TYROSINE HYDROX PSER40。
蛋白质印迹分析：
该批次的1:500稀释液在10 μg PC12裂解液中检测到TYROSINE HYDROX PSER40。
Application
免疫组化：
先前批次的1:1,000稀释液用于IH。
免疫细胞化学：
先前批次的1:1,000稀释液用于ELISA。
最佳工作稀释度必须由最终用户确定。
先前批次的1:1,000稀释液用于IH。
免疫细胞化学：
先前批次的1:1,000稀释液用于ELISA。
最佳工作稀释度必须由最终用户确定。
研究子类别
神经递质 & 受体
神经递质 & 受体
研究类别
神经科学
神经科学
酪氨酸羟化酶抗体（磷酸化Ser 40）可检测酪氨酸羟化酶水平& 已发表 & 经验证可用于IC、IH & WB。
Biochem/physiol Actions
其他物种尚未经过测试。
酪氨酸羟化酶，磷酸化Ser40。该抗体可识别60 kDa的蛋白质，对应于在Ser40处磷酸化的TH。根据所研究的大脑区域、蛋白质载量和使用的检测方法不同，可能会检测到一些分子量更高的条带。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
60 kDa
酪氨酸羟化酶在肾上腺素能神经元的生理中起重要作用。它是从酪氨酸生物合成儿茶酚胺多巴胺和去甲肾上腺素的第一种酶和限速酶。因此，TH是一种有用的多巴胺能和去甲肾上腺素能神经元标志物。TH酶活性维持需要亚铁离子作为辅因子，且人们普遍认为其受到磷酸化作用调控。目前至少鉴定出了四种因可变剪接而产生的人TH异构体。
Immunogen
来自大鼠酪氨酸羟化酶磷酸化Ser40的合成肽。
表位：磷酸化Ser40
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
免疫亲和纯化
纯化的兔多克隆抗体，液体，溶于含有10mM Hepes（pH 7.5）、150mM NaCl、100 µg/mL BSA和50%甘油的缓冲液中。
Preparation Note
自收到之日起，未稀释的等分试样可-20°C稳定保存6个月。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
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