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Merck
CN

ABN278

抗Prospero同源盒蛋白1/PROX1抗体

from rabbit, purified by affinity chromatography

别名:

Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
9
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

species reactivity (predicted by homology)

bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Prox1(19130)

General description

PROX1(Prospero同源盒蛋白1)是果蝇Prospero的同源物,是一种含有同源盒的转录因子,可结合并充当肝受体同源物1(LRH1/NR5A2)的共受体。它是淋巴内皮细胞以及成肝细胞和肝细胞的特异性标志物。人Prox1与小鼠和大鼠Prox1具有97%的氨基酸序列一致性。
观察值〜95 kDa。Uniprot描述了83kDa的分子量,然而,由于SUMO化和/或替代起始位点,可在80-110kDa之间观察到该蛋白(Pan,M.R.,et al.(2009).J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011).Genes Cells.16(11):1063-1070.)。

Immunogen

KLH偶联的线性肽,对应于人Prospero同源盒蛋白1/PROX1的C末端。

Application

免疫组化分析:代表性批次的1:2,000的稀释液在小鼠E16胚胎丘脑组织中检测到Prospero同源盒蛋白1/PROX1(Prof. Samual Pleasure, University of California, San Francisco.)。

Alexa Fluor是Life Technologies,Inc.的注册商标。
该抗Prospero同源盒蛋白1/PROX1抗体经验证可用于蛋白质印迹&IHC检测Prospero同源盒蛋白1/PROX1。

Analysis Note

通过蛋白质印迹在HEK293核提取物中进行了评估。

蛋白质印迹分析:该抗体的1:500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。

Other Notes

替代品:AB5475

Legal Information

ALEXA FLUOR is a trademark of Life Technologies


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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全球贸易项目编号

货号GTIN
ABN27804053252956720