biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, rat
species reactivity (predicted by homology)
bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Prox1(19130)
General description
PROX1(Prospero同源盒蛋白1)是果蝇Prospero的同源物,是一种含有同源盒的转录因子,可结合并充当肝受体同源物1(LRH1/NR5A2)的共受体。它是淋巴内皮细胞以及成肝细胞和肝细胞的特异性标志物。人Prox1与小鼠和大鼠Prox1具有97%的氨基酸序列一致性。
观察值〜95 kDa。Uniprot描述了83kDa的分子量,然而,由于SUMO化和/或替代起始位点,可在80-110kDa之间观察到该蛋白(Pan,M.R.,et al.(2009).J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011).Genes Cells.16(11):1063-1070.)。
Immunogen
KLH偶联的线性肽,对应于人Prospero同源盒蛋白1/PROX1的C末端。
Application
免疫组化分析:代表性批次的1:2,000的稀释液在小鼠E16胚胎丘脑组织中检测到Prospero同源盒蛋白1/PROX1(Prof. Samual Pleasure, University of California, San Francisco.)。
Alexa Fluor™是Life Technologies,Inc.的注册商标。
Alexa Fluor™是Life Technologies,Inc.的注册商标。
该抗Prospero同源盒蛋白1/PROX1抗体经验证可用于蛋白质印迹&IHC检测Prospero同源盒蛋白1/PROX1。
Analysis Note
通过蛋白质印迹在HEK293核提取物中进行了评估。
蛋白质印迹分析:该抗体的1:500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。
蛋白质印迹分析:该抗体的1:500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。
Other Notes
替代品:AB5475
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| ABN278 | 04053252956720 |