ABN363
抗髓磷脂蛋白P0抗体
from rabbit, purified by affinity chromatography
别名:
Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero
登录 查看组织和合同定价。
选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
rat, mouse
Citations:
6
Technique(s):
immunohistochemistry: suitable (paraffin)
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗髓磷脂蛋白P0抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse
species reactivity (predicted by homology)
bovine (based on 100% sequence homology), horse (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MPZ(4359)
相关类别
Analysis Note
通过蛋白质印迹对大鼠脊髓组织裂解物进行了评估。
蛋白质印迹分析：该抗体的1：5,000 的稀释液在 10 µg大鼠脊髓组织裂解物中检测到髓鞘蛋白P0。
蛋白质印迹分析：该抗体的1：5,000 的稀释液在 10 µg大鼠脊髓组织裂解物中检测到髓鞘蛋白P0。
Application
免疫组化分析：该抗体的1：2,000稀释液在大鼠脊髓切片中检测到髓鞘蛋白P0。
抗髓鞘蛋白P0抗体是一种高度特异性的兔多克隆抗体，其靶向髓鞘蛋白&已在蛋白质印迹& IHC（石蜡）中进行了测试。
研究子类别
发育神经科学
发育神经科学
研究类别
神经科学
神经科学
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
观察值〜30 kDa
髓鞘蛋白P0也称为外周髓鞘蛋白（MPP）和髓鞘蛋白零（MPZ）。髓鞘蛋白P0仅在外周神经系统中发现，并参与细胞外膜表面的形成，该表面引导包裹过程，最终促使相邻薄片的压实。髓鞘蛋白P0与多种疾病状态有关，包括Charcot-Marie-Tooth病1B（CMT1B），Charcot-Marie-Tooth病2I（CMT2I），Charcot-Marie-Tooth病2J（CMT2J），强直性瞳孔（ADIEP），Charcot-Marie-Tooth病，显性，中间型，D（CMTDID），德热里纳-索塔斯综合征（DSS），先天性髓鞘发育不良神经病（CHN）和Roussy-Levy综合征（ROULS）。
Immunogen
对应于人髓鞘蛋白P0胞外域的KLH偶联的线性肽。
Physical form
亲和纯化
在含 0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl 和 0.05％ 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
Preparation Note
自收到之日起，在 2-8°C 条件下可稳定保存1年
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Ying Zou et al.
Cell & bioscience, 11(1), 210-210 (2021-12-16)
Silent information regulator 6 (SIRT6) is a mammalian homolog of the nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin family. Prior evidences suggested that the anti-inflammatory function of SIRT6 after spinal cord and brain injury, and it plays a crucial role in
Ramazan Üstün et al.
Experimental and therapeutic medicine, 28(3), 345-345 (2024-07-29)
Traumatic and postoperative hemorrhages are life-threatening complications. Ankaferd BloodStopper (ABS) is a potent topical hemostatic agent to stop bleeding. However, ABS is associated with nerve toxicity. The present study aimed to investigate the functional and structural neurodegenerative effects of ABS
Sandra Murphy et al.
Journal of proteomics, 191, 212-227 (2018-02-07)
The highly progressive neuromuscular disorder dystrophinopathy is triggered by primary abnormalities in the Dmd gene, which causes cytoskeletal instability and loss of sarcolemmal integrity. Comparative organellar proteomics was employed to identify sarcolemma-associated proteins with an altered concentration in dystrophic muscle
Yan Guo et al.
Signal transduction and targeted therapy, 9(1), 32-32 (2024-02-14)
The appropriate and specific response of nerve cells to various external cues is essential for the establishment and maintenance of neural circuits, and this process requires the proper recruitment of adaptor molecules to selectively activate downstream pathways. Here, we identified
Jiawei Xu et al.
Journal of neuroinflammation, 18(1), 234-234 (2021-10-17)
Plenty of macrophages are recruited to the injured nerve to play key roles in the immunoreaction and engulf the debris of degenerated axons and myelin during Wallerian degeneration, thus creating a conducive microenvironment for nerve regeneration. Recently, drugs targeting the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持