ABS204
磷酸化-PDHE1-A I 型 (Ser293) 抗体
from rabbit, purified by affinity chromatography
别名:
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I
产品名称
磷酸化-PDHE1-A I 型 (Ser293) 抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
primate (based on 100% sequence homology), zebrafish (based on 100% sequence homology), rat (based on 100% sequence homology), bovine (based on 100% sequence homology), mouse (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer293)
Quality Level
Gene Information
human ... PDHA1(5160)
Analysis Note
对照
未经处理和经DCA处理的HEK293细胞裂解液
未经处理和经DCA处理的HEK293细胞裂解液
通过蛋白质印迹法对未经处理和经DCA处理的HEK293细胞裂解液进行了评估。
蛋白质印迹分析：该抗体的1:10,000稀释液在未经处理和经DCA处理的HEK293细胞裂解液中检测到磷酸化I型PDHE1-A（Ser293）。
蛋白质印迹分析：该抗体的1:10,000稀释液在未经处理和经DCA处理的HEK293细胞裂解液中检测到磷酸化I型PDHE1-A（Ser293）。
Application
免疫细胞化学分析：代表性批次抗体的1:500稀释液在未经处理和经DCA处理的HEK293细胞中检测到磷酸化PDHE1-A I型（Ser293）。
可使用这种磷酸化I型PDHE1-A（Ser293）抗体检测磷酸化I型PDHE1-A（Ser293），该抗体经验证可用于WB、IC & IP。
研究子类别
葡萄糖/糖原代谢
葡萄糖/糖原代谢
研究类别
代谢
代谢
Biochem/physiol Actions
该抗体可识别在Ser293处磷酸化的I型PDHE1-A。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
在许多生物体内，丙酮酸脱氢酶（PDH）复合物在有氧途径中催化丙酮酸整体不可逆地转化为乙酰辅酶A和CO2。这种复合物也是心脏底物选择的关键调节因子。它包含丙酮酸脱氢酶（E1或I型PDHE1-A）、二氢硫辛酰胺乙酰转移酶（E2）和硫辛酰胺脱氢酶（E3）三种酶组分的多个拷贝。PDH通过丙酮酸脱氢酶激酶（PDK）介导的磷酸化和反馈抑制调节。
观测值〜43 kDa
Immunogen
KLH偶联线性肽，对应于在Ser293处磷酸化的人I型PDHE1-A。
表位：磷酸化Ser293
Physical form
亲和纯化
纯化的兔多克隆抗体，溶于含有0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05％叠氮化钠的缓冲液中。
Preparation Note
自收到之日起，在2-8°C条件下可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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