产品名称
抗-TSLP抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TSLP(85480)
Analysis Note
对照
A20细胞裂解液
A20细胞裂解液
通过蛋白质印迹法在A20细胞裂解液中进行评价。
蛋白质印迹分析：2 µg/mL的该抗体在15 µg A20细胞裂解液中检测到TSLP。
蛋白质印迹分析：2 µg/mL的该抗体在15 µg A20细胞裂解液中检测到TSLP。
Application
使用经验证可用于蛋白质印迹，IHC（石蜡）&免疫荧光的该兔多克隆抗体（抗TSLP抗体）检测胸腺基质淋巴生成素。
免疫组化分析：代表性批次的1:1,000稀释液在人类前列腺癌和心脏组织中检测到TSLP。
免疫荧光分析： 20 μg/mL代表性批次在人大脑细胞中检测到TSLP。
免疫荧光分析： 20 μg/mL代表性批次在人大脑细胞中检测到TSLP。
研究子类别
粘附（CAMs）
粘附（CAMs）
研究类别
细胞结构
细胞结构
Biochem/physiol Actions
该抗体可识别TSLP的中间域。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
胸腺基质淋巴生成素（TSLP）最近被确定为能够驱动树突状细胞成熟和激活的重要因子。TSLP是一种主要由屏障上皮细胞表达的四螺旋束细胞因子，是多种细胞类型（如骨髓树突状细胞）的有效激活剂。TSLP参与调节性T细胞的正向选择、外周CD4+ T细胞稳态的维持和CD4+ T细胞介导过敏反应的诱导。TSLP还能够支持胎儿肝脏和成人B细胞祖细胞的生长，并支持它们向B细胞发育的IgM阳性阶段分化。TSLP在许多组织中表达，包括心脏、肝脏和前列腺。
观察值〜23 kDa。 该蛋白的计算分子量为18 kDa，但由于高糖基化，可以在〜23 kDa处观察到。
Immunogen
KLH偶联的线性肽，对应于人TSLP的中间域。
表位：中间域
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
在含有PBS和高达0.1%叠氮化钠的缓冲液中的纯化兔多克隆。
抗原亲和纯化
Preparation Note
自收到之日起，在2-8°C条件下可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Simon G Royce et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6402-6411 (2019-02-16)
The airway remodeling (AWR) associated with chronic allergic airways disease (AAD)/asthma contributes to irreversible airway obstruction. This study compared and combined the antiremodeling and other effects of induced pluripotent stem cell and mesenchymoangioblast-derived mesenchymal stem cells (MCA-MSCs) with the corticosteroid
Kathleen M Buchheit et al.
The Journal of allergy and clinical immunology, 137(5), 1566-1576 (2015-12-23)
Prostaglandin (PG) D2 is the dominant COX product of mast cells and is an effector of aspirin-induced respiratory reactions in patients with aspirin-exacerbated respiratory disease (AERD). We evaluated the role of the innate cytokine thymic stromal lymphopoietin (TSLP) acting on
Simon G Royce et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6402-6411 (2019-02-16)
The airway remodeling (AWR) associated with chronic allergic airways disease (AAD)/asthma contributes to irreversible airway obstruction. This study compared and combined the antiremodeling and other effects of induced pluripotent stem cell and mesenchymoangioblast-derived mesenchymal stem cells (MCA-MSCs) with the corticosteroid
Eda Ustaoglu et al.
Indian journal of dermatology, 68(2), 170-177 (2023-06-05)
This study aims to investigate the anti-inflammatory effects of cinnamaldehyde in atopic dermatitis (AD) in the mouse model. Twenty-four mice were divided into four groups: Group A (control), group B [AD with no treatment (AD + NoTre)], group C [AD
Amlan Chakraborty et al.
Biomaterials, 273, 120796-120796 (2021-04-25)
Asthma (chronic allergic airways disease, AAD) is characterized by airway inflammation (AI), airway remodeling (AWR) and airway hyperresponsiveness (AHR). Current treatments for AAD mainly focus on targeting AI and its contribution AHR, with the use of corticosteroids. However, there are
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