生物来源
rabbit
质量水平
偶联物
peroxidase conjugate
抗体形式
F(ab′)2 fragment of affinity isolated antibody
抗体产品类型
secondary antibodies
克隆
polyclonal
种属反应性
mouse
制造商/商品名称
Chemicon®
技术
ELISA: suitable
western blot: suitable
运输
wet ice
靶向翻译后修饰
unmodified
一般描述
免疫球蛋白G（IgG） 是在人类血清中发现的最丰富的糖蛋白抗体。它是由B细胞分泌的。IgG结构包含4条多肽链，其中包括两条相同的重（H）链和两条完全相同的λ轻（L）链。这些链通过二硫键相互连接。IgG以IgG1、IgG2、IgG3和IgG4四种亚型存在。
应用
兔抗小鼠IgG抗体，HRP偶联物已用于蛋白质印迹。(1:2000)(1:200000)(1:5000)
生化/生理作用
免疫球蛋白G（IgG）有助于补体系统的激活。它中和病毒颗粒和毒素。IgG促进抗体依赖性细胞介导的细胞毒性（ADCC）。母体IgG通过胎盘转移到 胎儿 ，这对于保护新生儿免受 传染病的侵害至关重要。检测严重急性呼吸系统综合征冠状病毒（SARS-CoV）2型感染患者的IgG水平可能是评估2019冠状病毒病（COVID-19）严重程度和预后的一种潜在策略。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury.
Roger S Chung, Paul A Adlard, Justin Dittmann, James C Vickers, Meng Inn Chuah, Adrian K West
Journal of Neurochemistry null
Elen Rizzi et al.
International journal of cardiology, 165(1), 165-173 (2011-09-16)
Increased oxidative stress upregulates matrix metalloproteinases (MMPs) and transforming grow factor (TGF-β), which are involved in hypertensive cardiac remodeling. We tested the hypothesis that tempol (an antioxidant) could prevent these alterations in two-kidney, one-clip (2K1C) hypertension. Sham-operated or hypertensive rats
Cristina Evangelisti et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(12), 4276-4287 (2009-08-29)
MicroRNAs are a class of sophisticated regulators of gene expression, acting as post-transcriptional inhibitors that recognize their target mRNAs through base pairing with short regions along the 3'UTRs. Several microRNAs are tissue specific, suggesting a specialized role in tissue differentiation
S B A Cau et al.
British journal of pharmacology, 164(2), 372-381 (2011-03-26)
Mounting evidence implicates matrix metalloproteinase (MMP) in the vascular dysfunction and remodelling associated with hypertension. We tested the hypothesis that treatment with pyrrolidine dithiocarbamate (PDTC), which interferes with NF-κB-induced MMPs gene transcription, could exert antihypertensive effects, prevent MMP-2 and MMP-9
Andrezza N Gonçalves et al.
Journal of biotechnology, 157(1), 20-24 (2011-10-18)
Characterization of the matrix metalloproteinase-2 (MMP-2) substrates and understanding of its function remain difficult because up to date preparations containing minor amounts of other eukaryotic proteins that are co-purified with MMP-2 are still used. In this work, the expression of
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持