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Merck
CN

AP500B

Goat Anti-Mouse IgM µ chain Antibody, biotin conjugate, Species Adsorbed

0.5 mg/mL, Chemicon®

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Conjugate:
biotin conjugate
Clone:
polyclonal
Application:
ELISA
Citations:
1
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biological source

goat

conjugate

biotin conjugate

antibody form

affinity purified immunoglobulin

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

concentration

0.5 mg/mL

technique(s)

ELISA: suitable

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

General description

IgM constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.

Immunogen

Epitope: IgM µ chain
Prepared from purified mouse IgM µ chain. Pooled antisera from goats hyperimmunized with mouse IgM paraproteins.

Application

ELISA: 1:5,000-1:20,000

Optimal working dilutions must be determined by the end user.
Research Category
Secondary & Control Antibodies
Research Sub Category
Secondary Antibodies Adsorbed for Dual Labeling

Fragment Specific Secondary Antibodies
This Goat anti-Mouse IgM µ chain Antibody, biotin conjugate, Species Adsorbed is validated for use in ELISA for the detection of Mouse IgM µ chain.

Biochem/physiol Actions

Reacts with heavy chain of mouse IgM. Absorbed for mouse IgG1, IgG2a, IgG2b, IgG3 and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins. Reactivity with other species has not been determined.
The antibody reacts with the heavy chain of mouse IgM as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.

Physical form

Affinity Chromatography
Purified by affinity chromatography on mouse IgM covalently linked to agarose. Liquid in 2.0 mL PBS/NaN3.

Preparation Note

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Lin Zhu et al.
Cardiovascular diabetology, 13, 151-151 (2014-11-14)
Diabetes accelerates atherosclerosis through undefined molecular mechanisms. Hyperglycemia induces formation of advanced glycation end product (AGE)-modified low-density lipoprotein (LDL). Anti-AGE-LDL autoantibodies favor atherosclerosis (AS) progression in humans, while anti oxidized LDL immunization inhibits AS in hypercholesterolemic, non-diabetic mice. We here

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