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Merck
CN

AP503H

Goat Anti-Chicken IgG (H+L) Antibody, PE conjugate

0.5 mg/mL, Chemicon®

别名:

IgY

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UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
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产品名称

Goat Anti-Chicken IgG (H+L) Antibody, PE conjugate, 0.5 mg/mL, Chemicon®

biological source

goat

conjugate

PE

antibody form

affinity purified immunoglobulin

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

chicken

manufacturer/tradename

Chemicon®

concentration

0.5 mg/mL

technique(s)

ELISA: suitable
immunofluorescence: suitable

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Application

Goat anti-Chicken IgG (H+L) Antibody, PE conjugate is an antibody against Chicken IgG (H+L) for use in ELISA & IF.
Immunofluorescence: ≤0.2 μg/106 cells.
ELISA

Optimal working dilutions must be determined by the end user.
Research Category
Secondary & Control Antibodies
Research Sub Category
Whole Immunoglobulin Secondary Antibodies

Biochem/physiol Actions

The antibody reacts with the heavy and light chains of chicken IgG as demonstrated by ELISA.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

IgG is one of the most abundant proteins in human serum. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Immunogen

Epitope: Chicken IgG
Prepared from pooled antisera from goats hyperimmunized with chicken IgG.

Physical form

Affinity Chromatography
Purified by affinity chromatography on chicken IgG covalently linked to agarose. Liquid in 1.0 mL of PBS/NaN3 and a stabilizing agent.

Preparation Note

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. DO NOT FREEZE.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Luke F Pennington et al.
Nature communications, 12(1), 7069-7069 (2021-12-05)
Antibody drugs exert therapeutic effects via a range of mechanisms, including competitive inhibition, allosteric modulation, and immune effector mechanisms. Facilitated dissociation is an additional mechanism where antibody-mediated "disruption" of stable high-affinity macromolecular complexes can potentially enhance therapeutic efficacy. However, this
Michelle Cristiane Bufalo et al.
Cells, 11(2) (2022-01-22)
Increased collagen-derived advanced glycation end-products (AGEs) are consistently related to painful diseases, including osteoarthritis, diabetic neuropathy, and neurodegenerative disorders. We have recently developed a model combining a two-dimensional glycated extracellular matrix (ECM-GC) and primary dorsal root ganglion (DRG) that mimicked

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