产品名称
Cellicon®过滤器组件，带Durapore®膜, filtration area 0.8 m2
material
PVDF membrane
polyester screen
polypropylene housing (polypropylene silicone)
silicone O-ring
sterility
non-sterile; γ-irradiated
storage condition
dry at room temperature
room temperature (15-30°C)
parameter
7.15 L/min-m2 flow rate
technique(s)
tangential flow filtration (TFF): suitable
D × W × H
12.2 cm (4.8 in) × 23.4 cm (9.2 in) × 37.6 cm (14.8 in)
filtration area
0.8 m2
volume
0.73 L , Filter Only
1.1 L , Assembly
1100 mL , Assembly
730 mL
matrix
Durapore®
pore size
5.0 μm
pH
4-8
application(s)
mAb
recombinant protein
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Application
Microfiltration and Seed Train Perfusion
Features and Benefits
- Predictable linear scalability from lab to manufacturing scale
- Reliable and reproducible performance
- Gentle on cells, maximizing cell density and viability
- Easy installation, with smooth connection to bioreactor through welding or sterile connectors
General description
The Cellicon® Filter Assembly is designed to meet your perfused seed train challenges. It is a flat sheet cell retention filter running in tangential flow filtration mode part of a single-use assembly. Perfusion operations deliver high-density cell cultures that alleviate the burden of processing large production bioreactor volumes while increasing manufacturing flexibility. Introducing perfusion to your seed train makes it possible to inoculate a higher quantity of cells for one or more production bioreactors, thus increasing process efficiency.
Other Notes
The Emprove® Program complements the product portfolio through comprehensive documentation to support qualification, risk assessment and process optimization needs.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.
Packaging
The Cellicon® filter packaging meets the requirements of the American Society for Testing and Materials (ASTM) Integrity Test Procedure D4169. The Cellicon® filter and assembly are secured in foam parts which is then double bagged. A caution label and a gamma indicator label are included on the inner bag. The double bagged Cellicon® filter Assembly is individually boxed. A Certificate of Quality is available electronically.
Legal Information
CELLICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Durapore is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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通过我们的细胞截留解决方案提升灌流种子培养效率。实时监测和控制。
Enhance perfused seed train efficiency with our cell retention solution. Real-time monitoring and control.
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