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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
FITC conjugate
Clone:
OX-42, monoclonal
Application:
flow cytometry
immunohistochemistry
immunohistochemistry
Species reactivity:
rat
Citations:
5
Technique(s):
flow cytometry: suitable
immunohistochemistry: suitable
immunohistochemistry: suitable
Uniprot accession no.:
产品名称
抗-整合素 αM [CD11b]抗体,克隆OX-42,FITC偶联, clone OX-42, Chemicon®, from mouse
biological source
mouse
conjugate
FITC conjugate
antibody product type
primary antibodies
clone
OX-42, monoclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Itgam(25021)
Biochem/physiol Actions
该抗体识别大多数巨噬细胞(包括常驻腹膜和活化巨噬细胞)、枯否细胞,但仅识别约35%的肺泡巨噬细胞。 该抗体还广泛标记大脑中的树突状细胞,粒细胞和具有小胶质细胞形态的细胞。该抗体沉淀150、103和95 kDa的三种多肽。该抗体可抑制补体介导的玫瑰花结,可能是IC3b的人类受体的大鼠等效物(称为CR3)。
融合伴侣:NSO骨髓瘤细胞系。
融合伴侣:NSO骨髓瘤细胞系。
Other Notes
替代:MAB1404F
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Application
流式细胞仪
高碘酸盐-赖氨酸-多聚甲醛(PLP)固定或丙酮后大鼠新鲜冷冻组织切片的免疫组织化学研究。 在非常轻微的PFA固定,冷冻组织上工作。(仅灌注4%PFA 10-15′,无后固定)。
最佳工作稀释度必须由最终用户进行确定。
高碘酸盐-赖氨酸-多聚甲醛(PLP)固定或丙酮后大鼠新鲜冷冻组织切片的免疫组织化学研究。 在非常轻微的PFA固定,冷冻组织上工作。(仅灌注4%PFA 10-15′,无后固定)。
最佳工作稀释度必须由最终用户进行确定。
经验证,该抗整合素αM CD11b抗体(克隆OX-42,FITC偶联)可用于FC,IH,以检测整合素αM[CD11b]。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Jaesuk Lee et al.
International journal of stem cells, 12(1), 114-124 (2019-03-07)
Parkinsons disease (PD) is a fatal and progressive degenerative disease of the nervous system. Until recently, its promising treatment and underlying mechanisms for neuronal death are poorly understood. This study was investigated to identify the molecular mechanism of neuronal death
Kyunghee Byun et al.
PloS one, 9(8), e104699-e104699 (2014-08-21)
Alcohol is a neurotoxic agent, since long-term heavy ingestion of alcohol can cause various neural diseases including fetal alcohol syndrome, cerebellar degeneracy and alcoholic dementia. However, the molecular mechanisms of alcohol-induced neurotoxicity are still poorly understood despite numerous studies. Thus
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