CBL186
抗DNA抗体,克隆AC-30-10
clone AC-30-10, Chemicon®, from mouse
别名:
Deoxyribonucleic acid
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
AC-30-10, monoclonal
Technique(s):
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
immunohistochemistry: suitable (paraffin)
Application:
immunofluorescence
immunohistochemistry
immunohistochemistry
Citations:
30
产品名称
抗DNA抗体,克隆AC-30-10, clone AC-30-10, Chemicon®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
AC-30-10, monoclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Chemicon®
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
isotype
IgM
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Application
因其可与任何形式的天然和变性DNA反应而研究（细胞生物学、分子生物学、微生物学）。免疫荧光检测中可用于检测培养细胞组织上DNA抗体，尤其是在自身抗体和自身免疫性疾病的诊断中的可靠阳性对照。
细胞培养中支原体污染的灵敏检测。
用于冷冻和石蜡组织切片。
最佳工作稀释度必须由最终用户进行确定。
细胞培养中支原体污染的灵敏检测。
用于冷冻和石蜡组织切片。
最佳工作稀释度必须由最终用户进行确定。
抗-DNA抗体AC-30-10克隆是一种用于DNA检测的小鼠单克隆抗体 & 已在IF、IHC(P)中得到验证。
研究子类别
细胞周期，DNA 复制&修复
细胞周期，DNA 复制&修复
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
该抗体可与从多种生物中提取的天然变性DNA发生反应：小鼠DNA、小牛胸腺DNA、M13 DNA、SV-40 DNA和数种质粒。 它还可以与不同碱基组成的合成DNA发生反应：聚dAT-聚dAT、聚dAT。还可识别来个自多个物种不同组织中以及如XLKE-A6（非洲爪蟾）、RVF-SMC（鼠袋鼠）和HeLa（人类）等不同细胞系中的含DNA结构，如染色质。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Physical form
形式：纯化
该免疫球蛋白是通过凝胶过滤进行纯化并保存在含0.09％叠氮化钠和0.5% BSA的pH 7.4 PBS中。
Preparation Note
自收到之日起，在2-8°C可最多保存12个月。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Andong Qin et al.
Cells, 12(21) (2023-11-10)
Coxsackievirus B3 (CVB3), a single-stranded positive RNA virus, primarily infects cardiac myocytes and is a major causative pathogen for viral myocarditis (VMC), driving cardiac inflammation and organ dysfunction. However, whether and how myocardial damage is involved in CVB3-induced VMC remains
Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.
Wang, YE; Marinov, GK; Wold, BJ; Chan, DC
Testing null
Sebastian Aguirre et al.
Nature microbiology, 2, 17037-17037 (2017-03-28)
During the last few decades, the global incidence of dengue virus (DENV) has increased dramatically, and it is now endemic in more than 100 countries. To establish a productive infection in humans, DENV uses different strategies to inhibit or avoid
Pedro Silva-Pinheiro et al.
Nucleic acids research, 49(9), 5230-5248 (2021-05-07)
Mutations in POLG, encoding POLγA, the catalytic subunit of the mitochondrial DNA polymerase, cause a spectrum of disorders characterized by mtDNA instability. However, the molecular pathogenesis of POLG-related diseases is poorly understood and efficient treatments are missing. Here, we generate
Mohammad T Hussan et al.
Current issues in molecular biology, 44(3), 1215-1223 (2022-06-21)
The presence of ectopic DNA in the cytoplasm induces inflammation and cell death. It has been widely reported that leakage of nuclear DNA into the cytoplasm can mainly be sensed by cyclic GMP-AMP synthase (cGAS). We recently reported that mitochondria-derived
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