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Merck
CN

CBL561

抗-CD24抗体,克隆SN3

clone SN3, Chemicon®, from mouse

别名:

Heat Stable Antigen, HAS

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
SN3, monoclonal
Application:
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
Species reactivity:
human
Citations:
10
Technique(s):
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
Uniprot accession no.:
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产品名称

抗-CD24抗体,克隆SN3, clone SN3, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

SN3, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CD24(100133941)

Application

在冷冻组织切片上进行免疫细胞化学分析:

流式细胞术: 1:50 - 1:100/10e6个细胞,最终体积为100 μL。

最佳工作稀释度必须由最终用户进行确定。
抗CD24抗体,克隆SN3检测CD24的水平&,经发布 & 验证可用于FC、IP、IH。
研究子类别
免疫球蛋白 & 免疫学
研究类别
炎症 & 免疫学

Biochem/physiol Actions

该抗体与CD24抗原反应,CD24抗原是一种高度糖基化的分子,在还原性和非还原性SDS凝胶电泳上均以35-45 kDa的宽条带迁移。 CD24通过糖基磷脂酰肌醇(GPI)锚附着在细胞膜上,并在B细胞发育的多个阶段表达,从骨髓CD34阳性pro-B细胞小室开始,一直持续到成熟的表面IgM阳性/IgD阳性B细胞。 CD24也表达于绝大多数B细胞系急性淋巴细胞白血病,B细胞慢性淋巴细胞白血病和B细胞非霍奇金′淋巴瘤。 在正常脾脏中,外套层淋巴细胞为CD24强阳性,但生发中心细胞为CD24阴性或CD24弱阳性。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Immunogen

从人NALM-1细胞系纯化的糖蛋白。

Other Notes

浓度:请参考批次特异性浓缩物的检验报告。

Physical form

形式:纯化
通过蛋白G层析法亲和纯化的免疫球蛋白。液体溶于1 mL PBS(pH 7.4),不含防腐剂。

Preparation Note

自收到之日起,未稀释等分试样在-20°C下可保存12个月。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Federico F Cifuentes et al.
Oncology reports, 34(6), 2837-2844 (2015-10-28)
Metastatic prostate cancer (mPCa) is one of the most prevalent cancers in men worldwide. The main cause of death in these patients is androgen-resistant metastatic disease. Surgery of the primary tumor has been avoided in these patients as there is
L Qiu et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 23(1), 245-250 (2011-04-26)
The size of the breast stem-cell pool could underlie the intrauterine roots of breast cancer. We studied whether breast stem cells exist in umbilical cord blood and if they correlate with hematopoietic stem-cell measurements that have been positively associated with
Yanmei Qi et al.
Scientific reports, 10(1), 12685-12685 (2020-07-31)
The epithelial-mesenchymal transition (EMT) is an embryonic program frequently reactivated during cancer progression and is implicated in cancer invasion and metastasis. Cancer cells can also acquire stem cell properties to self-renew and give rise to new tumors through the EMT.

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