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Merck
CN

CHGE71TS48

Millipore Express® SHC 0.5/0.2µm Cartridge 10

Code 7 Silicone, Autoclavable and SIP

别名:

Millipore Express SHC Cartridge Filter 10 in. 0.5/0.2 μm Code 7 Silicone, 48-pack

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UNSPSC Code:
23151806

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产品名称

Millipore Express® SHC Cartridge, Chemistry: 0.5 / 0.2 µm Hydrophilic Polyethersulfone (PES) Cartridge: 10 in. Code 7

Quality Level

400

cartridge code

Code 7

material

polyethersulfone membrane, polypropylene housing, polypropylene support, polysulfone (core), silicone O-ring

reg. compliance

meets FDA Indirect Food Additive requirements cited in 21 CFR 177-182 (all component materials)

sterility

non-sterile

sterilization compatibility

autoclavable compatible
steam-in-place compatible

product line

Millipore Express®

feature

hydrophilic

parameter

0.34 bar max. differential pressure (5 psi) at 135 °C (Forward), 1 bar max. differential pressure (15 psi) at 135 °C (Forward), 1.7 bar max. differential pressure (25 psi) at 80 °C (Forward), 2.1 bar max. differential pressure (30 psi) at 25 °C (Reverse), 6.9 bar max. differential pressure (100 psi) at 25 °C (Forward), 69 mbar max. differential pressure (1 psi) at 135 °C (Reverse)

technique(s)

sterile filtration: suitable

L

25.4 cm (10 in.)

diam.

6.9 in. (2.7 cm)

filtration area

0.48 m2 (5.2 ft2)

impurities

<0.25 EU/mL USP bacterial endotoxins (LAL test, sample aqueous extraction)

matrix

Millipore Express® SHC

pore size

0.5/0.2 μm pore size

bubble point

≥4000 mbar (58 psig), air with water at 23 °C

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General description

Device Configuration: Capsule

Application

Millipore Express® SHC (Sterile, High Capacity) filters provide superior throughput and capacity in applications where sterilizing-grade performance is needed and premature filter plugging is a concern. These filters are ideal for sterile filtration of cell culture media, protein solutions and other high fouling fluids. Millipore Express® SHC filters contain two polyethersulfone membrane layers, 0.5 µm/0.2 µm and come in a range of device formats and sizes to suit your application needs.

Features and Benefits

  • High capacity, high flux hydrophilic PES membranes
  • Validated sterilizing-grade performance
  • Easy wetting and integrity testing
  • Superior throughput in high fouling streams, including media and protein containing solutions
  • Increased capacity for improved process efficiency and economy
  • Broad chemical compatibility across a wide pH range
  • (1-14) — caustic compatible

Analysis Note

TOC/Conductivity
After sterilization and a controlled water flush of 20 L, samples exhibited less than 500 ppb TOC per USP <643> and less than 1.3 µS/cm per USP <645> at 25 °C.
Bacterial Retention


Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 107 CFU/cm² using ASTM® F838 methodology.

Other Notes

Directions for Use

  • Organism Retention: Microorganism
  • Mode of Action: Filtration (size exclusion)
  • Application: BioProcessing
  • Intended Use: Reduction or removal of microorganism/bioburden
  • Instructions for Use: Please refer to Millipore Express® Membrane user guide
  • Storage Statement: Please refer to Millipore Express® Membrane user guide
  • Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.


These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials
MILLIPORE EXPRESS is a registered trademark of Merck KGaA, Darmstadt, Germany

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