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Merck
CN

FCMAB412F

Milli-Mark® 抗胶原Ⅰ型-FITC抗体，克隆5D8-G9

clone 5D8-G9, Milli-Mark®, from mouse

别名:

Alpha-1 type I collagen

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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产品名称

Milli-Mark® 抗胶原Ⅰ型-FITC抗体，克隆5D8-G9, clone 5D8-G9, Milli-Mark®, from mouse

biological source

mouse

conjugate

FITC conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

5D8-G9, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1κ

NCBI accession no.

NP_000079

UniProt accession no.

P02452

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... COL1A1(1277)

相关类别

Analysis Note

对照
HEK293T细胞
通过流式细胞术对HEK293T细胞进行了评估。

Application

Milli-Mark抗胶原I-FITC抗体（克隆5D8-G9）是用于Fc的抗I型胶原抗体。
研究类别
细胞结构

Biochem/physiol Actions

抗体识别人I型胶原。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

胶原蛋白在整个进化过程中是高度保守的，其特征在于不间断的“甘氨酸X Y”三联体重复序列，其是三螺旋结构的必需部分。I型胶原蛋白（95 kDa）存在于骨骼，角膜，皮肤和肌腱中。编码基因的突变与成骨不全、埃勒斯-当洛斯综合征和特发性骨质疏松症有关。该基因和血小板衍生的生长因子β基因所在的染色体17和22之间的相互易位，与称为隆突性皮肤纤维肉瘤的特定类型的皮肤肿瘤有关，这是由于生长因子的表达不受调节所致。
计算值为139 kDa

Immunogen

在弗′氏完全佐剂中乳化的纯化人I型胶原。

Physical form

在含0.1％叠氮化钠和15 mg/mL BSA的PBS中与FITC偶联的纯化的小鼠单克隆IgG1。
蛋白A

Preparation Note

自收到之日起，未稀释等分试样避光冷藏于 2-8°C，可保存6个月。

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Tünde Mester et al.
PloS one, 11(9), e0162994-e0162994 (2016-09-16)
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Edmée Eyraud et al.
eLife, 12 (2023-07-26)
Bronchi of chronic obstructive pulmonary disease (COPD) are the site of extensive cell infiltration, allowing persistent contact between resident cells and immune cells. Tissue fibrocytes interaction with CD8+ T cells and its consequences were investigated using a combination of in
Chun-Yu Lo et al.
Respiratory research, 18(1), 194-194 (2017-11-23)
Patients with severe asthma have increased airway remodelling and elevated numbers of circulating fibrocytes with enhanced myofibroblastic differentiation capacity, despite being treated with high doses of corticosteroids, and long acting β2-adrenergic receptor (AR) agonists (LABAs). We determined the effect of
Tanya Wright et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 95(9), 997-1007 (2019-07-10)
Osteosarcoma (OSA) is a malignant tumor of middle-aged dogs and adolescent humans. The clinical outcome of OSA has not improved over more than three decades, and dogs typically succumb to metastatic disease within 6 months despite tumor resection through limb
T Maekawa et al.
Leukemia, 31(12), 2709-2716 (2017-04-08)
Myelofibrosis (MF) may be caused by various pathogenic mechanisms such as elevation in circulating cytokine levels, cellular interactions and genetic mutations. However, the underlying mechanism of MF still remains unknown. Recent studies have revealed that fibrocytes, the spindle-shaped fibroblast-like hematopoietic
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流式细胞分析实验方案主要步骤

了解流式细胞分析实验方案的主要步骤，以便轻松完成后续流式细胞分析实验。

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