生物来源
mouse
质量水平
偶联物
ALEXA FLUOR™ 488
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
113-1, monoclonal
种属反应性
human (mitochondria protein)
请勿与下列物质发生反应
mouse (mitochondria protein), rat (mitochondria protein)
技术
immunocytochemistry: suitable
同位素/亚型
IgG1
运输
wet ice
靶向翻译后修饰
unmodified
一般描述
计算值为60 kDa
该抗体可识别人细胞中线粒体的60 kDa非糖基化蛋白组分。它可用于染色细胞、组织或生化制剂中的线粒体，并可用作亚细胞组分中线粒体的标志物。MAB1273A4通过免疫沉淀识别65 kD的蛋白，并在人细胞的细胞质中产生条状的“意大利面条状”染色模式。
应用
使用经验证可用于ICC的小鼠单克隆抗体（抗线粒体抗体，克隆113-1 &Alexa Fluor™488偶联物）检测线粒体标记物。
通过免疫细胞化学在原代小鼠胚胎成纤维细胞（PMEF）中进行评估。
免疫细胞化学分析：该抗体的1：50稀释液未在原代小鼠胚胎成纤维细胞（PMEF）中检测到线粒体。
免疫细胞化学分析：该抗体的1：50稀释液未在原代小鼠胚胎成纤维细胞（PMEF）中检测到线粒体。
分析说明
通过免疫细胞化学在人脂肪间充质干细胞（SCC038）中进行评估。
免疫细胞化学分析：该抗体的1：50稀释液在人脂肪间充质干细胞（SCC038）中检测到线粒体。
免疫细胞化学分析：该抗体的1：50稀释液在人脂肪间充质干细胞（SCC038）中检测到线粒体。
其他说明
浓度：请参考批次特异性浓缩物的分析证书。
法律信息
ALEXA FLUOR is a trademark of Life Technologies
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Markus Pasztorek et al.
Frontiers in bioengineering and biotechnology, 7, 338-338 (2019-12-06)
The mechanobiological behavior of mesenchymal stem cells (MSCs) in two- (2D) or three-dimensional (3D) cultures relies on the formation of actin filaments which occur as stress fibers and depends on mitochondrial dynamics involving vimentin intermediate filaments. Here we investigate whether
Anna C Krieger et al.
Cancers, 15(10) (2023-06-22)
Cardiolipin (CL) is a mitochondrial lipid with diverse roles in cellular respiration, signaling, and organelle membrane structure. CL content and composition are essential for proper mitochondrial function. Deranged mitochondrial energy production and signaling are key components of glial cell cancers
Hao Chen et al.
Research (Washington, D.C.), 2021, 9798580-9798580 (2021-07-13)
Stem cell therapy holds high promises in regenerative medicine. The major challenge of clinical translation is to precisely and quantitatively evaluate the in vivo cell distribution, migration, and engraftment, which cannot be easily achieved by current techniques. To address this
Estelle Porret et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 182, 141-151 (2022-12-19)
Glioblastoma (GBM) is the most common and deadly form of primary brain tumor. Between 30 % and 60 % of GBM are characterized by overexpression of the Epidermal Growth Factor Receptor (EGFR). The anti-EGFR antibody Cetuximab (CTX) showed a favorable effect for
Wen Yang et al.
Cell, 167(4), 985-1000 (2016-11-25)
Mitochondrial sirtuins, SIRT3-5, are NAD+-dependent deacylases and ADP-ribosyltransferases that are critical for stress responses. However, a comprehensive understanding of sirtuin targets, regulation of sirtuin activity, and the relationships between sirtuins remains a key challenge in mitochondrial physiology. Here, we employ
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持