MAB1293
抗DNA抗体，双链，克隆AE-2
clone AE-2, Chemicon®, from mouse
别名:
双链DNA抗体
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
AE-2, monoclonal
Technique(s):
immunocytochemistry: suitable, immunohistochemistry: suitable
Application:
ICC, IHC
Citations:
33
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
AE-2, monoclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable
isotype
IgG3
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Immunogen
Raji Burkitt′s淋巴瘤细胞核
表位：双链
Application
免疫细胞化学：多聚甲醛固定细胞制剂
免疫组织化学：多聚甲醛固定冰冻组织切片
免疫组织化学 分析：检测到双链的代表性批次 1:50 稀释 人类前列腺和扁桃体组织切片中的 DNA。
最佳工作稀释度必须由最终用户进行确定。
免疫组织化学：多聚甲醛固定冰冻组织切片
免疫组织化学 分析：检测到双链的代表性批次 1:50 稀释 人类前列腺和扁桃体组织切片中的 DNA。
最佳工作稀释度必须由最终用户进行确定。
抗DNA抗体，双链，克隆AE-2是一种高质量的小鼠单克隆抗体，用于检测DNA&，已在ICC &IHC中进行了验证。
研究子类别
细胞周期，DNA 复制&修复
细胞周期，DNA 复制&修复
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
双链DNA。MAB1293在正常和恶性细胞的细胞核中产生均匀的染色模式。
Physical form
形式：纯化
纯化的免疫球蛋白。 0.02M磷酸盐缓冲液，0.25M NaCl和0.1%叠氮化钠的液体。
Preparation Note
以未稀释的等分试样保存于2-8°C下6个月。
Analysis Note
对照
阳性对照：人扁桃体
阳性对照：人扁桃体
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Manuel Adrian Suter et al.
Scientific reports, 11(1), 7243-7243 (2021-04-02)
Deficiencies in DNA repair and DNA degrading nucleases lead to accumulation of cytosolic DNA. cGAS is a critical DNA sensor for the detection of cytosolic DNA and subsequent activation of the STING signaling pathway. Here, we show that the cGAS-STING
Yang Liu et al.
Scientific reports, 6, 18696-18696 (2016-01-05)
Iridovirid infection is associated with the catastrophic loss in aquaculture industry and the population decline of wild amphibians and reptiles, but none of the iridovirid life cycles have been well explored. Here, we report the detailed visualization of the life
Lateral elements inside synaptonemal complex-like polycomplexes in ndt80 mutants of yeast bind DNA.
Bhuiyan, H; Dahlfors, G; Schmekel, K
Genetics null
Sangita Khatri et al.
Journal of translational autoimmunity, 3, 100068-100068 (2020-11-19)
Neuropsychiatric systemic lupus erythematosus is an autoimmune disorder characterized by an irregular exchange between the central nervous system and the immune system, leading to the outbreak of neurological conditions with possible disabling effects. Although neuropsychiatric systemic lupus erythematosus is the
Xiaoli Wu et al.
Theranostics, 10(13), 5749-5762 (2020-06-03)
Chronic inflammation is known to promote carcinogenesis; Dicer heterozygous mice are more likely to develop colitis-associated tumors. This study investigates whether Dicer is downregulated in inflamed colon tissues before malignancy occurs and whether increasing Dicer expression in inflamed colon tissues
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