MAB1587
抗谷氨酸转运蛋白抗体，神经元，克隆4D6.2
clone 4D6.2, Chemicon®, from mouse
别名:
EAAT3
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4D6.2, monoclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
rat
Citations:
8
Technique(s):
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗谷氨酸转运蛋白抗体，神经元，克隆4D6.2, clone 4D6.2, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
4D6.2, monoclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC1A1(6505)
相关类别
Application
抗谷氨酸转运蛋白抗体，神经元，克隆4D6.2是用于IH &WB的针对谷氨酸转运蛋白的抗体。
研究子类别
神经递质& 受体
神经递质& 受体
研究类别
神经科学
神经科学
蛋白质印迹：1-2 μg/mL
免疫组化：1-2 μg/mL
最佳工作稀释度必须由最终用户进行确定。
EAAC1约为66-70kDa；蛋白也可以在制备过程中形成同型多聚体，因此经常也可以看到200-220kDa的大条带。
免疫组化：1-2 μg/mL
最佳工作稀释度必须由最终用户进行确定。
EAAC1约为66-70kDa；蛋白也可以在制备过程中形成同型多聚体，因此经常也可以看到200-220kDa的大条带。
Biochem/physiol Actions
谷氨酸转运蛋白EAAC1。
基于蛋白序列，该抗体预期可与小鼠、牛和兔反应。
基于蛋白序列，该抗体预期可与小鼠、牛和兔反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
C端肽（KDKSDTISFTQTSQF）（目录号AG372）。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
形式：纯化
纯化的免疫球蛋白。 溶液形式，溶于0.02M磷酸盐缓冲液（pH 7.6）、0.25M NaCl、和0.1％叠氮化钠中。
Preparation Note
可在2-8°C保存长达6个月。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Clozapine-induced reduction of glutamate transport in the frontal cortex is not mediated by GLAST and EAAC1.
M Melone et al.
Molecular psychiatry, 8(1), 12-13 (2003-01-31)
Bárbara Coimbra et al.
Nature communications, 10(1), 4138-4138 (2019-09-14)
The laterodorsal tegmentum (LDT) is associated with reward considering that it modulates VTA neuronal activity, but recent anatomical evidence shows that the LDT also directly projects to nucleus accumbens (NAc). We show that the majority of LDT-NAc inputs are cholinergic
Han-Byeol Kim et al.
Cell death discovery, 6, 73-73 (2020-08-21)
Neonatal maternal separation (NMS), as an early-life stress (ELS), is a risk factor to develop emotional disorders. However, the exact mechanisms remain to be defined. In the present study, we investigated the mechanisms involved in developing emotional disorders caused by
M C Medrano et al.
British journal of pharmacology, 169(8), 1781-1794 (2013-05-04)
Excitatory amino acid transporters (EAATs) in the CNS contribute to the clearance of glutamate released during neurotransmission. The aim of this study was to explore the role of EAATs in the regulation of locus coeruleus (LC) neurons by glutamate. We
Han-Byeol Kim et al.
Molecular brain, 13(1), 153-153 (2020-11-15)
Excitatory amino acid carrier 1 (EAAC1) is an important subtype of excitatory amino acid transporters (EAATs) and is the route for neuronal cysteine uptake. CoCl2 is not only a hypoxia-mimetic reagent but also an oxidative stress inducer. Here, we found
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