MAB1919
抗原纤蛋白抗体，克隆11C1.3
clone 11C1.3, Chemicon®, from mouse
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
11C1.3, monoclonal
Application:
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Species reactivity:
bovine, pig, human
Citations:
18
Technique(s):
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗原纤蛋白抗体，克隆11C1.3, clone 11C1.3, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
11C1.3, monoclonal
species reactivity
bovine, pig, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FBN1(2200)
Application
免疫印迹：抗体与牛主动脉平滑肌细胞释放的35万Da蛋白反应，该蛋白与原纤维蛋白相同。
免疫组化：新鲜冷冻组织：1:200-1:500。石蜡切片经微波柠檬酸盐缓冲液抗原提取后有反应。
免疫沉淀：5微升抗体稀释在不超过400微升的牛平滑肌细胞浓缩上清液中。我们建议使用抗小鼠IgG抗体头或兔抗小鼠捕获抗体，然后使用蛋白A。A.
ELISA
最佳稀释度必须由最终用户确定。
免疫组化：新鲜冷冻组织：1:200-1:500。石蜡切片经微波柠檬酸盐缓冲液抗原提取后有反应。
免疫沉淀：5微升抗体稀释在不超过400微升的牛平滑肌细胞浓缩上清液中。我们建议使用抗小鼠IgG抗体头或兔抗小鼠捕获抗体，然后使用蛋白A。A.
ELISA
最佳稀释度必须由最终用户确定。
抗纤原蛋白抗体，克隆11C1.3是用于ELISA、IF、IP、WB、IH(P)的抗纤原蛋白抗体。
研究子类别
ECM 蛋白
ECM 蛋白
研究类别
细胞结构
细胞结构
Biochem/physiol Actions
牛带状原纤维。与人弹性蛋白微原纤维反应良好，可用于马凡氏患者或从这些患者获得的成纤维细胞中研究这些原纤维的存在和组织。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
牛带状原纤维
Physical form
形式：纯化
液体
Preparation Note
以未稀释的等分试样保存于-20°C下12个月。应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
A common variant rs2054564 in ADAMST17 is associated with susceptibility to lumbar spondylosis.
Taniguchi, et al.
Scientific Reports, 13, 4900-4900 (2023)
Hannah L Bader et al.
Matrix biology : journal of the International Society for Matrix Biology, 31(7-8), 398-411 (2012-09-27)
ADAMTS-like proteins are related to ADAMTS metalloproteases by their similarity to ADAMTS ancillary domains. Here, we have characterized ADAMTSL5, a novel member of the superfamily with a unique modular organization that includes a single C-terminal netrin-like (NTR) module. Alternative splicing
ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.
Kutz, WE; Wang, LW; Bader, HL; Majors, AK; Iwata, K; Traboulsi, EI; Sakai, LY; Keene, DR; Apte, SS
The Journal of Biological Chemistry null
Mohamed A Sideek et al.
Matrix biology : journal of the International Society for Matrix Biology, 34, 114-123 (2013-10-24)
Latent transforming growth factor-beta-1 binding protein-2 (LTBP-2) is a protein of ill-defined function associated with elastic fibers during elastinogenesis. Although LTBP-2 binds fibrillin-1, fibulin-5, and heparin/heparan sulfate, molecules critical for normal elastic fiber assembly, it does not interact directly with
Eric Hanssen et al.
The Journal of biological chemistry, 279(28), 29185-29194 (2004-05-08)
The interactions of microfibril-associated glycoprotein (MAGP)-2 have been investigated with fibrillins and fibrillin-containing microfibrils. Solid phase binding assays were conducted with recombinant fragments covering fibrillin-1 and most of fibrillin-2. MAGP-2, and its structure relative MAGP-1, were found to bind two
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