biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
8F6.2, monoclonal
species reactivity
monkey, fish, rabbit
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
rabbit ... Gjd2(100341036)
Application
使用经验证可用于IH的抗连接蛋白35/36抗体(克隆8F6.2)检测连接蛋白35/36。
Biochem/physiol Actions
可识别鲈鱼连接蛋白35。不与连接蛋白34.7(一种密切相关的蛋白)发生交叉反应。还识别兔和猕猴连接蛋白36,即连接蛋白35的基因同源物。在免疫组化中标记鲈鱼,兔子和猕猴视网膜中的间隙连接。
Physical form
形式:纯化
纯化的免疫球蛋白。 液体溶于含50%甘油的0.1 M柠檬酸盐缓冲液中,还含有0.1%叠氮化钠作为防腐剂
Other Notes
替代品:MAB3044
浓度:请参考批次特异性浓缩物的分析证书。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Elena Ivanova et al.
Frontiers in cellular neuroscience, 9, 390-390 (2015-10-21)
Retinal degeneration (RD) encompasses a family of diseases that lead to photoreceptor death and visual impairment. Visual decline due to photoreceptor cell loss is further compromised by emerging spontaneous hyperactivity in inner retinal cells. This aberrant activity acts as a
Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids.
Cachope, R; Mackie, K; Triller, A; O'Brien, J; Pereda, AE
Neuron null
Adenosine and dopamine receptors coregulate photoreceptor coupling via gap junction phosphorylation in mouse retina.
Li, H; Zhang, Z; Blackburn, MR; Wang, SW; Ribelayga, CP; O'Brien, J
The Journal of Neuroscience null
Distribution of the gap junction protein connexin 35 in the central nervous system of developing zebrafish larvae.
Jabeen, S; Thirumalai, V
Frontiers in Neural Circuits null
Shuo Zhang et al.
Investigative ophthalmology & visual science, 61(6), 24-24 (2020-06-13)
The present study tested the hypothesis that connexin-36 (Cx36) and gap junctions between photoreceptor cells contribute to the circadian rhythm of the photopic electroretinogram (ERG) b-wave amplitude. Cone-specific disruption of Cx36 was obtained in mice with a floxed Gjd2 gene
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