MAB3868
抗-DNA抗体，单链
clone TNT-3, Chemicon®, from mouse
别名:
ssDNA
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
TNT-3, monoclonal
Technique(s):
ELISA: suitable, flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin)
Application:
ELISA, FACS, ICC, IHC
Citations:
27
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
TNT-3, monoclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin)
isotype
IgG1, kappa
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Immunogen
人Raji细胞核
Application
使用经验证可用于ELISA、FC、IC、IH(P)的单链抗DNA抗体检测DNA。
多聚甲醛固定细胞的免疫细胞化学
多聚甲醛或B5固定组织切片的免疫组织化学。
流式细胞术：5-10 mg/mL，使用2%多聚甲醛固定细胞。
ELISA
最佳工作稀释度必须由最终用户确定。
染色模式：
染色细胞核的异染色质区。
多聚甲醛或B5固定组织切片的免疫组织化学。
流式细胞术：5-10 mg/mL，使用2%多聚甲醛固定细胞。
ELISA
最佳工作稀释度必须由最终用户确定。
染色模式：
染色细胞核的异染色质区。
研究子类别
细胞器&细胞标志物
细胞器&细胞标志物
研究类别
表位标记&一般用途
表位标记&一般用途
Biochem/physiol Actions
与单链DNA（ssDNA）反应。该抗体可用于染色有核细胞。该抗体还可用于识别肿瘤和受损组织的坏死区域。通过免疫组织化学，染色细胞核的异染色质区。
Physical form
不含防腐剂的 PBS 中的纯化的小鼠单克隆抗体 IgG1。
形式：纯化
Preparation Note
自接收之日起，以未稀释的等分试样在-20°C下保存长达6个月。应避免反复冻/融循环。
Other Notes
浓度：关于批次特定浓度请参见检验报告。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Fan Guo et al.
Cell stem cell, 15(4), 447-459 (2014-09-16)
The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embryogenesis to establish full developmental potential. Previous studies have suggested that the paternal genome is actively demethylated in the zygote while the maternal
Yunpeng Feng et al.
The EMBO journal, 35(2), 176-192 (2015-12-02)
During DNA replication, thousands of replication origins are activated across the genome. Chromatin architecture contributes to origin specification and usage, yet it remains unclear which chromatin features impact on DNA replication. Here, we perform a RNAi screen for chromatin regulators
Paula Andrea Marin et al.
Frontiers in cell and developmental biology, 8, 602956-602956 (2021-01-09)
DNA double-strand breaks (DSBs) are among the most deleterious lesions that threaten genome integrity. To address DSBs, eukaryotic cells of model organisms have evolved a complex network of cellular pathways that are able to detect DNA damage, activate a checkpoint
Christiane B de Araujo et al.
The Journal of eukaryotic microbiology, 66(3), 514-518 (2018-08-05)
Here, we investigated the features of replication in Trypanosoma cruzi epimastigotes based on fork speed progression, which is influenced by distinct features such as DNA polymerase rate, susceptibility to DNA damage and repair, secondary structures, transcription and chromatin state. Although
Ailing Lu et al.
Arthritis & rheumatology (Hoboken, N.J.), 73(8), 1467-1477 (2021-02-10)
Systemic lupus erythematosus (SLE) involves kidney damage, and the inflammasome-caspase-1 axis has been demonstrated to promote renal pathogenesis. The present study was designed to explore the function of the Absent in Melanoma 2 (Aim2) protein in SLE. Female wild-type Aim2-/-
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