产品名称
抗-阶段特异性胚胎抗原-3抗体,克隆MC-631, clone MC-631, from rat
biological source
rat
antibody form
purified antibody
antibody product type
primary antibodies
clone
MC-631, monoclonal
species reactivity
human
species reactivity (predicted by homology)
mouse
technique(s)
flow cytometry: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
isotype
IgMκ
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Other Notes
Physical form
Preparation Note
Disclaimer
General description
Immunogen
Analysis Note
流式细胞术分析: 1.0 µg该抗体在H9细胞中检测到阶段特异性胚胎抗原-3。
Application
免疫细胞化学分析:一个代表性批次通过荧光免疫细胞化学在T
细胞来源的iPSC(TiPSC)中检测到SSEA-3免疫反应性(Kishino,Y.,et al.(2014).PLoS One.9(5):e97397)。
免疫细胞化学分析:一个代表性批次通过荧光免疫细胞化学在培养的HCT116结肠直肠癌(CRC)细胞中检测到SSEA-3阳性癌症干细胞(CSC)的存在(Suzuki,Y.,et al.(2013).Int. J. Oncol.42(1):161-167)。
免疫细胞化学分析:一个代表性批次通过荧光免疫细胞化学检测到来自人臼齿来源的间充质基质细胞(MSC)的诱导多能干(iPS)细胞中的SSEA-3免疫反应性(Oda,Y.,et al.(2010).J. Biol. Chem. 285(38):29270-29278)。
流式细胞术分析: 一个代表性批次在五种培养的结直肠癌(CRC)细胞系HCT116、Caco-2、DLD-1、HT-29和SW480中检测到SSEA-3阳性癌症干细胞(CSC)的存在(Suzuki,Y.,et al.(2013).Int. J. Oncol.42(1):161-167)。
免疫荧光分析:一个代表性批次通过使用冷冻组织切片的荧光免疫组织化学检测到正常结肠直肠上皮细胞中大量的SSEA-3阳性基质细胞和结肠直肠腺癌中的SSEA-3阳性癌症(Suzuki,Y.,et al.(2013).Int. J. Oncol.42(1):161-167)。
细胞周期、DNA复制&修复
干细胞研究
Biochem/physiol Actions
未找到合适的产品?
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
"Mods – modifications – small alterations can have a big impact on form and function. In the motorsports world, stock vehicles are modified to enhance their performance. Modifications, or mods, to the engine, drive train, intake and exhaust components add up to provide phenomenal performance gains that can be measured as horsepower and torque increases, which yield a competitive advantage, and result in reduced run times. In biology, proteins undergo modifications that alter their function. Some proteins require the modifications in order to perform their function effectively, whether it’s a pro-protein that is cleaved to produce an active enzyme, or a protein that is phosphorylated to facilitate a signaling process. Other proteins, such as histones, undergo modifications that regulate gene expression and alter cellular function. There are several post translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination that impact protein function and activity. As a result, the analysis of proteins and their post-translational modifications are particularly important for the study of normal and disease-associated processes. New antibodies to detect phospho Histidines are now available from EMD Millipore."
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持