MABC60
抗-KiSS-1抗体，克隆8H4.1
clone 8H4.1, from mouse
别名:
Metastasis-suppressor KiSS-1, Kisspeptin-1, Metastin, Kisspeptin-542, Kisspeptin-143, Kisspeptin-134, Kisspeptin-10
产品名称
抗-KiSS-1抗体，克隆8H4.1, clone 8H4.1, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
8H4.1, monoclonal
species reactivity
human, rat
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... KISS1(3814)
Analysis Note
通过免疫组织化学在人胎盘组织中进行评价。
免疫组织化学分析：该抗体以1:1,000稀释度在人胎盘组织中检测到KiSS-1。
免疫组织化学分析：该抗体以1:1,000稀释度在人胎盘组织中检测到KiSS-1。
Application
免疫组织化学分析：一个代表性批次以1:1,000稀释度在人胰腺和大鼠睾丸组织中检测到KiSS-1。
抗KiSS-1抗体，克隆8H4.1是针对KiSS-1的抗体，用于IHC、蛋白质印迹。
General description
计算分子量15 kDa
转移抑制因子KiSS-1（KiSS-1；或Kisspeptin-1）是孤儿G蛋白偶联受体GPR54的几种内源性配体之一。KiSS-1通过抑制受影响细胞的迁移和增殖，在各种类型的癌症中起着抑制转移的作用。这种作用可能是由多种信号通路的激活产生的: 配体结合的GPR54通过PLC途径激活IP3和PKC信号传导；以及cPLA2引起的ERK 1和ERK 2，这可能分别导致钙信号传导和基因转录增加。然而，最近，KiSS-1/GPR54信号传导与青春期和发育有关。KISS-1/GPR54可能在青春期调节GnRH神经元的信号传导，并可能影响FH和LSH激素的释放。KISS-1在中枢神经系统、睾丸、胰腺、肠、卵巢和胎盘中高度表达。
Immunogen
对应于人KiSS-1的重组蛋白。
Other Notes
浓度：关于批次特定浓度请参见检验报告。
Physical form
形式：纯化
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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